STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSc0985Probable aminotransferase, classIand II; protein. (406 aa)    
Predicted Functional Partners:
RSc0229
Probable transcriptional regulators containing a dna-binding hth domain and an aminotransferase domain transcription regulator protein.
  
  
 
0.908
gcvP
Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family.
   
 
 0.907
RSc1326
Probable aspartate aminotransferase protein.
   
 0.906
glyA1
Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.903
RSc1034
Hypothetical oxidoreductase protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.903
glyA2
Probable serine hydroxymethyltransferase 2 (serine methylase 2)(shmt 2) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism.
    
 0.903
RSp0945
Probable dehydrogenase oxidoreductase protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family.
  
 
  0.903
RSc0262
Probable d-isomer specific 2-hydroxyacid dehydrogenase, nad-binding; oxidoreductase protein.
    
  0.901
gcvT
Probable aminomethyltransferase (glycine cleavage system tprotein); The glycine cleavage system catalyzes the degradation of glycine.
  
 
  0.901
RSc1271
Probable dihydrolipoamide dehydrogenase (component of pyruvate and 2-oxoglutarate dehydrogenases complexes) oxidoreductase protein.
     
  0.900
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.