| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc2160 | ampG | RSc2160 | RSc0154 | Putative xanthosine triphosphate pyrophosphatase protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Transport transmembrane protein. | 0.744 |
| RSc2160 | rpoE1 | RSc2160 | RSc1055 | Putative xanthosine triphosphate pyrophosphatase protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | 0.621 |
| ampG | RSc2160 | RSc0154 | RSc2160 | Transport transmembrane protein. | Putative xanthosine triphosphate pyrophosphatase protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.744 |
| ampG | rpoE1 | RSc0154 | RSc1055 | Transport transmembrane protein. | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | 0.613 |
| fis | rpoE1 | RSc0505 | RSc1055 | Putative fis-like dna-binding. transcription regulator protein; Belongs to the transcriptional regulatory Fis family. | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | 0.618 |
| recO | rpoE1 | RSc1065 | RSc1055 | Probable dna repair protein reco (recombination protein o); Involved in DNA repair and RecF pathway recombination. | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | 0.583 |
| recO | rseA | RSc1065 | RSc1056 | Probable dna repair protein reco (recombination protein o); Involved in DNA repair and RecF pathway recombination. | Putative transmembrane sigma-e factor negative regulatory transcription regulator protein. | 0.435 |
| recO | rseB | RSc1065 | RSc1057 | Probable dna repair protein reco (recombination protein o); Involved in DNA repair and RecF pathway recombination. | Putative sigma-e factor regulatory (negative regulator) transcription regulator protein. | 0.470 |
| rpoB | rpoC | RSc3034 | RSc3033 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Probable dna-directed rna polymerase (beta' chain) protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoB | rpoE1 | RSc3034 | RSc1055 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | 0.573 |
| rpoB | rpoN2 | RSc3034 | RSp1671 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Probable rna polymerase sigma n (sigma 54) factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.807 |
| rpoB | rpoZ | RSc3034 | RSc2154 | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.998 |
| rpoC | rpoB | RSc3033 | RSc3034 | Probable dna-directed rna polymerase (beta' chain) protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.999 |
| rpoC | rpoE1 | RSc3033 | RSc1055 | Probable dna-directed rna polymerase (beta' chain) protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | 0.581 |
| rpoC | rpoN2 | RSc3033 | RSp1671 | Probable dna-directed rna polymerase (beta' chain) protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | Probable rna polymerase sigma n (sigma 54) factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. | 0.801 |
| rpoC | rpoZ | RSc3033 | RSc2154 | Probable dna-directed rna polymerase (beta' chain) protein; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.998 |
| rpoE1 | RSc2160 | RSc1055 | RSc2160 | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | Putative xanthosine triphosphate pyrophosphatase protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.621 |
| rpoE1 | ampG | RSc1055 | RSc0154 | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | Transport transmembrane protein. | 0.613 |
| rpoE1 | fis | RSc1055 | RSc0505 | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | Putative fis-like dna-binding. transcription regulator protein; Belongs to the transcriptional regulatory Fis family. | 0.618 |
| rpoE1 | recO | RSc1055 | RSc1065 | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | Probable dna repair protein reco (recombination protein o); Involved in DNA repair and RecF pathway recombination. | 0.583 |