STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSc1058Probable periplasmic protease signal peptide protein; Belongs to the peptidase S1C family. (505 aa)    
Predicted Functional Partners:
RSp1552
Probable protease signal peptide protein; Belongs to the peptidase S1C family.
  
  
 
0.907
rseA
Putative transmembrane sigma-e factor negative regulatory transcription regulator protein.
  
 
 0.863
RSc1059
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
  
   0.797
glpK
Probable glycerol kinase (atp:glycerol 3-phosphotransferase)(glycerokinase) (gk) protein; Key enzyme in the regulation of glycerol uptake and metabolism. Catalyzes the phosphorylation of glycerol to yield sn- glycerol 3-phosphate; Belongs to the FGGY kinase family.
   
 0.659
hemE
Probable uroporphyrinogen decarboxylase (uro-d) (upd) protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
      
 0.656
RSc2138
Putative helix-turn-helix, hxlr type; transcription regulator protein.
      
 0.639
rseB
Putative sigma-e factor regulatory (negative regulator) transcription regulator protein.
  
  
 0.624
lepB
Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family.
 
   
 0.613
RSp0641
Probable non ribosomal peptide synthetase protein.
  
 
 0.579
lepA
Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner.
 
  
 0.548
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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