| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc1062 | lepA | RSc1062 | RSc1060 | Probable transmembrane protein. | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.684 |
| RSc1062 | lepB | RSc1062 | RSc1061 | Probable transmembrane protein. | Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family. | 0.685 |
| RSc1062 | rnc | RSc1062 | RSc1063 | Probable transmembrane protein. | Probable ribonuclease III (rnase III) protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.857 |
| RSc1716 | lepA | RSc1716 | RSc1060 | Putative signal peptidaseI(spaseI protein; Belongs to the peptidase S26 family. | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.669 |
| RSc1716 | lepB | RSc1716 | RSc1061 | Putative signal peptidaseI(spaseI protein; Belongs to the peptidase S26 family. | Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family. | 0.918 |
| RSc1716 | lspA | RSc1716 | RSc2459 | Putative signal peptidaseI(spaseI protein; Belongs to the peptidase S26 family. | Probable lipoprotein signal peptidase; This protein specifically catalyzes the removal of signal peptides from prolipoproteins; Belongs to the peptidase A8 family. | 0.789 |
| RSc1716 | oxaA | RSc1716 | RSc0004 | Putative signal peptidaseI(spaseI protein; Belongs to the peptidase S26 family. | Putative preprotein translocase subunit yidc transmembrane; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.802 |
| RSc1716 | rimO | RSc1716 | RSc1636 | Putative signal peptidaseI(spaseI protein; Belongs to the peptidase S26 family. | Putative 2-methylthioadenine synthetase protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.682 |
| RSc1716 | rnc | RSc1716 | RSc1063 | Putative signal peptidaseI(spaseI protein; Belongs to the peptidase S26 family. | Probable ribonuclease III (rnase III) protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.645 |
| RSc1716 | secY | RSc1716 | RSc2999 | Putative signal peptidaseI(spaseI protein; Belongs to the peptidase S26 family. | Probable preprotein translocase secy (membrane subunit) transmembrane; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may [...] | 0.797 |
| icmF | lepA | RSc0237 | RSc1060 | Putative methylmalonyl-coa mutase protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.575 |
| icmF | lepB | RSc0237 | RSc1061 | Putative methylmalonyl-coa mutase protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family. | 0.762 |
| lepA | RSc1062 | RSc1060 | RSc1062 | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Probable transmembrane protein. | 0.684 |
| lepA | RSc1716 | RSc1060 | RSc1716 | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Putative signal peptidaseI(spaseI protein; Belongs to the peptidase S26 family. | 0.669 |
| lepA | icmF | RSc1060 | RSc0237 | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Putative methylmalonyl-coa mutase protein; Catalyzes the reversible interconversion of isobutyryl-CoA and n-butyryl-CoA, using radical chemistry. Also exhibits GTPase activity, associated with its G-protein domain (MeaI) that functions as a chaperone that assists cofactor delivery and proper holo-enzyme assembly. | 0.575 |
| lepA | lepB | RSc1060 | RSc1061 | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family. | 0.935 |
| lepA | oxaA | RSc1060 | RSc0004 | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Putative preprotein translocase subunit yidc transmembrane; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.457 |
| lepA | rimO | RSc1060 | RSc1636 | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Putative 2-methylthioadenine synthetase protein; Catalyzes the methylthiolation of an aspartic acid residue of ribosomal protein S12; Belongs to the methylthiotransferase family. RimO subfamily. | 0.450 |
| lepA | rnc | RSc1060 | RSc1063 | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Probable ribonuclease III (rnase III) protein; Digests double-stranded RNA. Involved in the processing of primary rRNA transcript to yield the immediate precursors to the large and small rRNAs (23S and 16S). Processes some mRNAs, and tRNAs when they are encoded in the rRNA operon. Processes pre-crRNA and tracrRNA of type II CRISPR loci if present in the organism. | 0.840 |
| lepA | rpoH | RSc1060 | RSc0374 | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | Probable rna polymerase sigma h (sigma-32) factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is involved in regulation of expression of heat shock genes. | 0.482 |