STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
cobB-2Putative nad-dependent protein deacetylase; NAD-dependent lysine deacetylase and desuccinylase that specifically removes acetyl and succinyl groups on target proteins. Modulates the activities of several proteins which are inactive in their acylated form; Belongs to the sirtuin family. Class III subfamily. (246 aa)    
Predicted Functional Partners:
RSp0835
Putative bifunctional nmn adenylyltransferase/nudix hydrolase : nicotinamide-nucleotide adenylyltransferase and adp compounds hydrolase protein; Belongs to the Nudix hydrolase family.
 
 
 0.970
nadE
Probable nh3-dependent nad+ synthetase signal peptide protein; Catalyzes the ATP-dependent amidation of deamido-NAD to form NAD. Uses L-glutamine as a nitrogen source.
   
 0.951
nadD
Probable nicotinate-nucleotide adenylyltransferase; Catalyzes the reversible adenylation of nicotinate mononucleotide (NaMN) to nicotinic acid adenine dinucleotide (NaAD).
   
 0.939
ppnK
Putative inorganic polyphosphate/atp-nad kinase (poly(p)/atp nad kinase) protein; Involved in the regulation of the intracellular balance of NAD and NADP, and is a key enzyme in the biosynthesis of NADP. Catalyzes specifically the phosphorylation on 2'-hydroxyl of the adenosine moiety of NAD to yield NADP.
  
 
 0.926
RSp0836
Probable nicotinate phosphoribosyltransferase-related protein; Belongs to the NAPRTase family.
  
 0.924
pncA
Probable bifunctional protein: pyrazinamidase and nicotinamidase hydrolase (nicotine deamidase).
  
 0.914
pntAa
Probable nad(p) transhydrogenase (alpha subunit part 1) oxidoreductase protein.
     
 0.907
pntAa2
Probable nad(p) transhydrogenase (alpha subunit part 1) oxidoreductase protein.
     
 0.907
RSc2548
Putative inosine-uridine preferring nucleoside hydrolase transmembrane protein.
   
 
 0.906
pntAb
Probable transmembrane nad(p) transhydrogenase (alpha subunit part 2) protein.
     
 0.905
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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