close STRING v12.5 is now available!
The next version of STRING is ready for use in your analyses: updated networks across STRING • newly available directed regulatory networks • a new typed view showing functional, physical, and regulatory edges in one network • new clustering options and cluster-based layouts • … and much more!
Explore STRING v12.5 →
STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ntrBProbable nitrogen regulation (sensor protein kinase) transcription regulator. (361 aa)    
Predicted Functional Partners:
ntrC
Probable nitrogen assimilation regulatory response regulator transcription regulator protein; Member of the two-component regulatory system NtrB/NtrC, which controls expression of the nitrogen-regulated (ntr) genes in response to nitrogen limitation. Phosphorylated NtrC binds directly to DNA and stimulates the formation of open promoter-sigma54-RNA polymerase complexes.
 0.998
glnB
Probable nitrogen regulatory p-II transcription regulator protein; Belongs to the P(II) protein family.
  
 0.968
RSp0531
Probable p-II-related protein transcription regulator.
  
 0.968
glnD
Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...]
  
 
 
 0.855
amtB
Probable ammonium transporter transmembrane protein.
  
 
 0.826
vsrB
Composite two-component regulatory (sensor kinase and response regulator hybrid) transcription regulator protein.
 
 
 0.747
glnA1
Probable glutamine synthetase protein.
  
  
 0.720
glnK
Probable nitrogen regulatory p-II transcription regulator protein; Belongs to the P(II) protein family.
  
 
 0.698
RSc3079
Probable composite two component regulatory (sensor histidine kinase and response regulator hybrid) transcription regulator protein.
 
 
 
 0.644
pehR
Probable response regulator transcription regulator protein.
 
 0.642
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.