node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSc1982 | lexA | RSc1982 | RSc1304 | Probable dna-methyltransferase (dna-modification methylase) protein; Belongs to the N(4)/N(6)-methyltransferase family. | Probable lexa repressor. transcription regulator protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.698 |
RSp0798 | RSp0799 | RSp0798 | RSp0799 | Miscellaneous; hypothetical/partial homology. | Putative nucleotidyltransferase/dna polymerase involved in dna repair protein. | 0.998 |
RSp0798 | dinB | RSp0798 | RSc1587 | Miscellaneous; hypothetical/partial homology. | Probable dna polymerase iv (pol iv) protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | 0.795 |
RSp0798 | dnaE2 | RSp0798 | RSp0800 | Miscellaneous; hypothetical/partial homology. | Probable dna polymerase III (alpha chain) protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.978 |
RSp0798 | lexA | RSp0798 | RSc1304 | Miscellaneous; hypothetical/partial homology. | Probable lexa repressor. transcription regulator protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.738 |
RSp0798 | recN | RSp0798 | RSc2651 | Miscellaneous; hypothetical/partial homology. | Probable dna repair protein; May be involved in recombinational repair of damaged DNA. | 0.471 |
RSp0799 | RSp0798 | RSp0799 | RSp0798 | Putative nucleotidyltransferase/dna polymerase involved in dna repair protein. | Miscellaneous; hypothetical/partial homology. | 0.998 |
RSp0799 | dnaE2 | RSp0799 | RSp0800 | Putative nucleotidyltransferase/dna polymerase involved in dna repair protein. | Probable dna polymerase III (alpha chain) protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.972 |
RSp0799 | lexA | RSp0799 | RSc1304 | Putative nucleotidyltransferase/dna polymerase involved in dna repair protein. | Probable lexa repressor. transcription regulator protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.818 |
RSp0799 | recA | RSp0799 | RSc0551 | Putative nucleotidyltransferase/dna polymerase involved in dna repair protein. | Probable protein reca (recombinase a); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.; Belongs to the RecA family. | 0.756 |
dinB | RSp0798 | RSc1587 | RSp0798 | Probable dna polymerase iv (pol iv) protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Miscellaneous; hypothetical/partial homology. | 0.795 |
dinB | dnaE2 | RSc1587 | RSp0800 | Probable dna polymerase iv (pol iv) protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Probable dna polymerase III (alpha chain) protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | 0.783 |
dinB | lexA | RSc1587 | RSc1304 | Probable dna polymerase iv (pol iv) protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Probable lexa repressor. transcription regulator protein; Represses a number of genes involved in the response to DNA damage (SOS response), including recA and lexA. In the presence of single-stranded DNA, RecA interacts with LexA causing an autocatalytic cleavage which disrupts the DNA-binding part of LexA, leading to derepression of the SOS regulon and eventually DNA repair. | 0.954 |
dinB | mutM | RSc1587 | RSc0399 | Probable dna polymerase iv (pol iv) protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Formamidopyrimidine-DNA glycosylase; Involved in base excision repair of DNA damaged by oxidation or by mutagenic agents. Acts as DNA glycosylase that recognizes and removes damaged bases. Has a preference for oxidized purines, such as 7,8-dihydro-8-oxoguanine (8-oxoG). Has AP (apurinic/apyrimidinic) lyase activity and introduces nicks in the DNA strand. Cleaves the DNA backbone by beta-delta elimination to generate a single-strand break at the site of the removed base with both 3'- and 5'-phosphates. | 0.694 |
dinB | recA | RSc1587 | RSc0551 | Probable dna polymerase iv (pol iv) protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Probable protein reca (recombinase a); Can catalyze the hydrolysis of ATP in the presence of single- stranded DNA, the ATP-dependent uptake of single-stranded DNA by duplex DNA, and the ATP-dependent hybridization of homologous single-stranded DNAs. It interacts with LexA causing its activation and leading to its autocatalytic cleavage.; Belongs to the RecA family. | 0.873 |
dinB | recN | RSc1587 | RSc2651 | Probable dna polymerase iv (pol iv) protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Probable dna repair protein; May be involved in recombinational repair of damaged DNA. | 0.521 |
dinB | recX | RSc1587 | RSc0552 | Probable dna polymerase iv (pol iv) protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Putative regulatory protein recx; Modulates RecA activity.; Belongs to the RecX family. | 0.694 |
dinB | uvrC | RSc1587 | RSc1071 | Probable dna polymerase iv (pol iv) protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII. | Probable excinuclease abc subunit c (sos response dna repair protein); The UvrABC repair system catalyzes the recognition and processing of DNA lesions. UvrC both incises the 5' and 3' sides of the lesion. The N-terminal half is responsible for the 3' incision and the C-terminal half is responsible for the 5' incision. | 0.704 |
dnaE2 | RSp0798 | RSp0800 | RSp0798 | Probable dna polymerase III (alpha chain) protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | Miscellaneous; hypothetical/partial homology. | 0.978 |
dnaE2 | RSp0799 | RSp0800 | RSp0799 | Probable dna polymerase III (alpha chain) protein; DNA polymerase involved in damage-induced mutagenesis and translesion synthesis (TLS). It is not the major replicative DNA polymerase. | Putative nucleotidyltransferase/dna polymerase involved in dna repair protein. | 0.972 |