STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
dnaBProbable replicative dna helicase protein; Participates in initiation and elongation during chromosome replication; it exhibits DNA-dependent ATPase activity and contains distinct active sites for ATP binding, DNA binding, and interaction with DnaC protein, primase, and other prepriming proteins. Belongs to the helicase family. DnaB subfamily. (473 aa)    
Predicted Functional Partners:
dnaG
Probable dna primase protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication.
 0.962
dnaA
Probable chromosomal replication initiator protein dnaa; Plays an important role in the initiation and regulation of chromosomal replication. Binds to the origin of replication; it binds specifically double-stranded DNA at a 9 bp consensus (dnaA box): 5'- TTATC[CA]A[CA]A-3'. DnaA binds to ATP and to acidic phospholipids.
 
 
 0.943
RSc0967
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
  
 0.885
ssb
Probable single-strand binding protein (ssb) (helix-destabilizing protein); Plays an important role in DNA replication, recombination and repair. Binds to ssDNA and to an array of partner proteins to recruit them to their sites of action during DNA metabolism.
 
 0.830
uvrD
Probable dna helicase II protein.
 
 
 0.820
rplI
Probable 50s ribosomal protein l9; Binds to the 23S rRNA.
 
  
 0.813
priB
Probable primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
   
 0.809
dnaX
Probable dna polymerase III (subunits tau and gamma) protein; DNA polymerase III is a complex, multichain enzyme responsible for most of the replicative synthesis in bacteria. This DNA polymerase also exhibits 3' to 5' exonuclease activity.
 
 
 0.805
tISRso6b
Isrso6-transposase orfb protein.
  
 
 0.779
tISRso6b-2
Isrso6-transposase orfb protein.
  
 
 0.779
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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