| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0948 | RSp1116 | RSc0948 | RSp1116 | Putative amino-acid dehydratase protein. | Putative low specificity l-threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.909 |
| RSc0948 | ilvA | RSc0948 | RSc0449 | Putative amino-acid dehydratase protein. | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 0.926 |
| RSc0948 | ilvC | RSc0948 | RSc2075 | Putative amino-acid dehydratase protein. | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.608 |
| RSc0948 | ltaA | RSc0948 | RSc0808 | Putative amino-acid dehydratase protein. | Probable low specificity l-threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.909 |
| RSc0948 | thrC | RSc0948 | RSc1328 | Putative amino-acid dehydratase protein. | Probable threonine synthase protein. | 0.939 |
| RSc1327 | ilvC | RSc1327 | RSc2075 | Probable homoserine dehydrogenase oxidoreductase protein. | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.487 |
| RSc1327 | lysC | RSc1327 | RSc1171 | Probable homoserine dehydrogenase oxidoreductase protein. | Probable aspartate kinase protein; Belongs to the aspartokinase family. | 0.991 |
| RSc1327 | serC | RSc1327 | RSc0903 | Probable homoserine dehydrogenase oxidoreductase protein. | Probable phosphoserine aminotransferase (psat) protein; Catalyzes the reversible conversion of 3- phosphohydroxypyruvate to phosphoserine and of 3-hydroxy-2-oxo-4- phosphonooxybutanoate to phosphohydroxythreonine; Belongs to the class-V pyridoxal-phosphate-dependent aminotransferase family. SerC subfamily. | 0.460 |
| RSc1327 | thrB | RSc1327 | RSc2233 | Probable homoserine dehydrogenase oxidoreductase protein. | Probable homoserine kinase (hsk) (hk) protein; Belongs to the pseudomonas-type ThrB family. | 0.933 |
| RSc1327 | thrC | RSc1327 | RSc1328 | Probable homoserine dehydrogenase oxidoreductase protein. | Probable threonine synthase protein. | 0.990 |
| RSp1116 | RSc0948 | RSp1116 | RSc0948 | Putative low specificity l-threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Putative amino-acid dehydratase protein. | 0.909 |
| RSp1116 | ilvA | RSp1116 | RSc0449 | Putative low specificity l-threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 0.909 |
| RSp1116 | ltaA | RSp1116 | RSc0808 | Putative low specificity l-threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Probable low specificity l-threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.908 |
| RSp1116 | thrC | RSp1116 | RSc1328 | Putative low specificity l-threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | Probable threonine synthase protein. | 0.923 |
| ilvA | RSc0948 | RSc0449 | RSc0948 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Putative amino-acid dehydratase protein. | 0.926 |
| ilvA | RSp1116 | RSc0449 | RSp1116 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Putative low specificity l-threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.909 |
| ilvA | ilvC | RSc0449 | RSc2075 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | 0.561 |
| ilvA | ltaA | RSc0449 | RSc0808 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Probable low specificity l-threonine aldolase protein; Catalyzes the cleavage of L-allo-threonine and L-threonine to glycine and acetaldehyde. | 0.909 |
| ilvA | thrC | RSc0449 | RSc1328 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Probable threonine synthase protein. | 0.939 |
| ilvC | RSc0948 | RSc2075 | RSc0948 | Ketol-acid reductoisomerase (NADP(+)); Involved in the biosynthesis of branched-chain amino acids (BCAA). Catalyzes an alkyl-migration followed by a ketol-acid reduction of (S)-2-acetolactate (S2AL) to yield (R)-2,3-dihydroxy-isovalerate. In the isomerase reaction, S2AL is rearranged via a Mg-dependent methyl migration to produce 3-hydroxy-3-methyl-2-ketobutyrate (HMKB). In the reductase reaction, this 2-ketoacid undergoes a metal-dependent reduction by NADPH to yield (R)-2,3-dihydroxy-isovalerate. | Putative amino-acid dehydratase protein. | 0.608 |
