node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSc1401 | glnD | RSc1401 | RSc1402 | Miscellaneous; hypothetical/partial homology; Belongs to the pseudouridine synthase RsuA family. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.717 |
RSc1401 | map | RSc1401 | RSc1403 | Miscellaneous; hypothetical/partial homology; Belongs to the pseudouridine synthase RsuA family. | Probable methionine aminopeptidase protein; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.496 |
RSp0531 | amtB | RSp0531 | RSc0343 | Probable p-II-related protein transcription regulator. | Probable ammonium transporter transmembrane protein. | 0.914 |
RSp0531 | glnB | RSp0531 | RSc2345 | Probable p-II-related protein transcription regulator. | Probable nitrogen regulatory p-II transcription regulator protein; Belongs to the P(II) protein family. | 0.917 |
RSp0531 | glnD | RSp0531 | RSc1402 | Probable p-II-related protein transcription regulator. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.976 |
RSp0531 | gltB | RSp0531 | RSc2965 | Probable p-II-related protein transcription regulator. | Probable glutamate synthase (large subunit) oxidoreductase protein. | 0.537 |
RSp0531 | ntrB | RSp0531 | RSc1260 | Probable p-II-related protein transcription regulator. | Probable nitrogen regulation (sensor protein kinase) transcription regulator. | 0.968 |
amtB | RSp0531 | RSc0343 | RSp0531 | Probable ammonium transporter transmembrane protein. | Probable p-II-related protein transcription regulator. | 0.914 |
amtB | glnB | RSc0343 | RSc2345 | Probable ammonium transporter transmembrane protein. | Probable nitrogen regulatory p-II transcription regulator protein; Belongs to the P(II) protein family. | 0.995 |
amtB | glnD | RSc0343 | RSc1402 | Probable ammonium transporter transmembrane protein. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.549 |
amtB | glnE | RSc0343 | RSc2656 | Probable ammonium transporter transmembrane protein. | Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] | 0.481 |
amtB | glnK | RSc0343 | RSc0342 | Probable ammonium transporter transmembrane protein. | Probable nitrogen regulatory p-II transcription regulator protein; Belongs to the P(II) protein family. | 0.998 |
amtB | gltB | RSc0343 | RSc2965 | Probable ammonium transporter transmembrane protein. | Probable glutamate synthase (large subunit) oxidoreductase protein. | 0.791 |
amtB | ntrB | RSc0343 | RSc1260 | Probable ammonium transporter transmembrane protein. | Probable nitrogen regulation (sensor protein kinase) transcription regulator. | 0.826 |
bamA | glnD | RSc1412 | RSc1402 | Putative outer membrane signal peptide protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.646 |
bamA | map | RSc1412 | RSc1403 | Putative outer membrane signal peptide protein; Part of the outer membrane protein assembly complex, which is involved in assembly and insertion of beta-barrel proteins into the outer membrane. | Probable methionine aminopeptidase protein; Removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met-Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Requires deformylation of the N(alpha)-formylated initiator methionine before it can be hydrolyzed; Belongs to the peptidase M24A family. Methionine aminopeptidase type 1 subfamily. | 0.489 |
glnB | RSp0531 | RSc2345 | RSp0531 | Probable nitrogen regulatory p-II transcription regulator protein; Belongs to the P(II) protein family. | Probable p-II-related protein transcription regulator. | 0.917 |
glnB | amtB | RSc2345 | RSc0343 | Probable nitrogen regulatory p-II transcription regulator protein; Belongs to the P(II) protein family. | Probable ammonium transporter transmembrane protein. | 0.995 |
glnB | glnD | RSc2345 | RSc1402 | Probable nitrogen regulatory p-II transcription regulator protein; Belongs to the P(II) protein family. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.974 |
glnB | gltB | RSc2345 | RSc2965 | Probable nitrogen regulatory p-II transcription regulator protein; Belongs to the P(II) protein family. | Probable glutamate synthase (large subunit) oxidoreductase protein. | 0.537 |