STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpEPropionyl-coenzyme a synthetase prpe protein. (632 aa)    
Predicted Functional Partners:
prpC
Probable methylcitrate synthase (citrate synthase 2) protein; Belongs to the citrate synthase family.
  
 0.948
RSp0651
Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein.
  
  
 
0.925
RSp1265
Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein.
  
  
 
0.925
RSc2536
Putative transmembrane aldehyde dehydrogenase oxidoreductase protein.
   
 0.924
mmsA
Probable methylmalonate-semialdehyde dehydrogenase oxidoreductase protein.
   
 0.924
RSp1055
Probable transmembrane aldehyde dehydrogenase oxidoreductase protein.
   
 0.924
RSc0274
Probable acyl coa dehydrogenase oxidoreductase protein.
   
 
 0.914
acsA
Probable acetyl-coenzyme a synthetase (acetate--coa ligase) (acyl-activating enzyme) protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 
0.910
RSc0471
Putative coenzyme a transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
     
 0.906
RSc2891
Putative ipr002085 alcohol dehydrogenase superfamily, zinc-containing oxidoreductase protein.
   
 
 0.904
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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