STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
prpEPropionyl-coenzyme a synthetase prpe protein. (632 aa)    
Predicted Functional Partners:
prpC
Probable methylcitrate synthase (citrate synthase 2) protein; Belongs to the citrate synthase family.
  
 0.925
RSp0651
Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein.
  
  
 
0.925
RSp1265
Probable acetyl-coenzyme a synthetase (acetate--coa ligase) protein.
  
  
 
0.925
RSc0471
Putative coenzyme a transferase; CoA transferase having broad substrate specificity for short- chain acyl-CoA thioesters with the activity decreasing when the length of the carboxylic acid chain exceeds four carbons. Belongs to the 3-oxoacid CoA-transferase family.
     
 0.911
acsA
Probable acetyl-coenzyme a synthetase (acetate--coa ligase) (acyl-activating enzyme) protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
  
 
0.910
RSc2536
Putative transmembrane aldehyde dehydrogenase oxidoreductase protein.
   
 0.910
mmsA
Probable methylmalonate-semialdehyde dehydrogenase oxidoreductase protein.
   
 0.910
RSp1055
Probable transmembrane aldehyde dehydrogenase oxidoreductase protein.
   
 0.910
RSc0274
Probable acyl coa dehydrogenase oxidoreductase protein.
   
 
 0.905
RSc1799
Putative dihydrolipoamide acetyltransferase (component e2 of pyruvate dehydrogenase complex) protein.
  
 
 0.905
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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