Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
carBProbable carbamoyl-phosphate synthase large chain (carbamoyl-phosphate synthetase ammonia chain) protein. (1081 aa)    
Predicted Functional Partners:
pyrB
Probable aspartate carbamoyltransferase (aspartatetranscarbamylase) (atcase) protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
 
 0.999
carA
Probable carbamoyl-phosphate synthase small chain (carbamoyl-phosphate synthetase glutamine chain) protein; Belongs to the CarA family.
 0.999
argF
Probable ornithine carbamoyltransferase (otcase) protein; Reversibly catalyzes the transfer of the carbamoyl group from carbamoyl phosphate (CP) to the N(epsilon) atom of ornithine (ORN) to produce L-citrulline; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. OTCase family.
 
 
 0.996
pyrX
Probable dihydroorotase-like protein.
 
 0.994
purF
Probable amidophosphoribosyltransferase protein; Catalyzes the formation of phosphoribosylamine from phosphoribosylpyrophosphate (PRPP) and glutamine; In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family.
 
 
 0.987
argG
Probable argininosuccinate synthase (citrulline--aspartateligase) protein; Belongs to the argininosuccinate synthase family. Type 2 subfamily.
 
 0.983
pyrD
Probable dihydroorotate dehydrogenase oxidoreductase protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
 
 
 0.974
gltB
Probable glutamate synthase (large subunit) oxidoreductase protein.
  
 
 0.965
pyrE
Orotate phosphoribosyltransferase protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
  
 
 0.947
glmS
Glutamine--fructose-6-phosphate aminotransferase [isomerizing]; Catalyzes the first step in hexosamine metabolism, converting fructose-6P into glucosamine-6P using glutamine as a nitrogen source.
   
 0.944
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: high (94%) [HD]