STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
hflBProbable atp-dependent zinc metallopeptidase (cell division ftsh) transmembrane protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (628 aa)    
Predicted Functional Partners:
RSc1222
Putative membrane protease subunits, stomatin/prohibitin homologs transmembrane protein; HflC and HflK could encode or regulate a protease.
  
 0.970
rrmJ
Probable ribosomal rna large subunit methyltransferase j (cell division protein ftsj); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
 
  
 0.900
folE
Putative gtp cyclohydrolaseI(gtp-chI protein.
 
  
 0.884
tilS
Conserved hypothetical protein; Ligates lysine onto the cytidine present at position 34 of the AUA codon-specific tRNA(Ile) that contains the anticodon CAU, in an ATP-dependent manner. Cytidine is converted to lysidine, thus changing the amino acid specificity of the tRNA from methionine to isoleucine. Belongs to the tRNA(Ile)-lysidine synthase family.
    
 0.878
rpmA
Probable 50s ribosomal protein l27; Belongs to the bacterial ribosomal protein bL27 family.
 
 
 0.877
RSc1223
Putative serine protease transmembrane protein; HflC and HflK could regulate a protease.
  
 0.868
RSc0145
Putative membrane protease subunit, stomatin/prohibitin homolog transmembrane protein.
  
 0.867
rpsE
Probable 30s ribosomal protein s5; With S4 and S12 plays an important role in translational accuracy.; Belongs to the universal ribosomal protein uS5 family.
  
 
 0.865
rpsG
Probable 30s ribosomal protein s7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.; Belongs to the universal ribosomal protein uS7 family.
  
   0.859
rpsI
Probable 30s ribosomal protein s9; Belongs to the universal ribosomal protein uS9 family.
 
 
 0.855
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: low (20%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.