STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hflBProbable atp-dependent zinc metallopeptidase (cell division ftsh) transmembrane protein; Acts as a processive, ATP-dependent zinc metallopeptidase for both cytoplasmic and membrane proteins. Plays a role in the quality control of integral membrane proteins; Belongs to the AAA ATPase family. In the central section; belongs to the AAA ATPase family. (628 aa)    
Predicted Functional Partners:
rrmJ
Probable ribosomal rna large subunit methyltransferase j (cell division protein ftsj); Specifically methylates the uridine in position 2552 of 23S rRNA at the 2'-O position of the ribose in the fully assembled 50S ribosomal subunit.
 
  
 0.971
RSc1222
Putative membrane protease subunits, stomatin/prohibitin homologs transmembrane protein; HflC and HflK could encode or regulate a protease.
  
 0.955
atpA
Probable atp synthase alpha chain protein; Produces ATP from ADP in the presence of a proton gradient across the membrane. The alpha chain is a regulatory subunit. Belongs to the ATPase alpha/beta chains family.
   
 0.924
clpX
Probable atp-dependent clp protease atp-binding subunit clpx protein; ATP-dependent specificity component of the Clp protease. It directs the protease to specific substrates. Can perform chaperone functions in the absence of ClpP.
  
  
 0.902
hprT
Probable hypoxanthine phosphoribosyltransferase transmembrane protein.
  
  
 0.890
folE
Putative gtp cyclohydrolaseI(gtp-chI protein.
 
  
 0.888
rpsA
Probable 30s ribosomal subunit protein s1; Binds mRNA; thus facilitating recognition of the initiation point. It is needed to translate mRNA with a short Shine-Dalgarno (SD) purine-rich sequence.
  
   0.882
rpsG
Probable 30s ribosomal protein s7; One of the primary rRNA binding proteins, it binds directly to 16S rRNA where it nucleates assembly of the head domain of the 30S subunit. Is located at the subunit interface close to the decoding center, probably blocks exit of the E-site tRNA.; Belongs to the universal ribosomal protein uS7 family.
  
   0.881
rpsE
Probable 30s ribosomal protein s5; With S4 and S12 plays an important role in translational accuracy.; Belongs to the universal ribosomal protein uS5 family.
  
 
 0.876
RSc1223
Putative serine protease transmembrane protein; HflC and HflK could regulate a protease.
  
 0.872
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.