STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
metYProbable o-acetylhomoserine (thiol)-lyase (methionine/homocysteine synthase) protein. (444 aa)    
Predicted Functional Partners:
metX
Homoserine O-succinyltransferase; Transfers a succinyl group from succinyl-CoA to L-homoserine, forming succinyl-L-homoserine.
 
 0.993
metHa
Probable 5-methyltetrahydrofolate--homocysteine methyltransferase (methionine synthase, vitamin-b12 dependent isozyme) protein.
  
 
 0.966
ahcY
Probable adenosylhomocysteinase (s-adenosyl-l-homocysteinehydrolase) (adohcyase) protein; May play a key role in the regulation of the intracellular concentration of adenosylhomocysteine.
     
 0.964
metHb
Methionine synthase; Catalyzes the transfer of a methyl group from methyl- cobalamin to homocysteine, yielding enzyme-bound cob(I)alamin and methionine. Subsequently, remethylates the cofactor using methyltetrahydrofolate.
  
 
 0.960
RSp0781
Probable cystathionine beta-lyases/cystathionine gamma-synthases protein.
 
 
 0.960
metE
5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase; Catalyzes the transfer of a methyl group from 5- methyltetrahydrofolate to homocysteine resulting in methionine formation; Belongs to the vitamin-B12 independent methionine synthase family.
  
 
 0.949
metC
Putative cystathionine beta-lyase (cysteine lyase) protein.
 
 
0.939
RSc1840
Putative aminotransferase protein.
   
 0.919
RSp1583
Probable o-acetylhomoserine sulfhydrylase transmembrane protein.
  
  
 
0.917
RSc3313
Putative coa-binding protein.
      0.905
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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