| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| alaS | guaA | RSc0797 | RSc1431 | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | 0.703 |
| alaS | ileS | RSc0797 | RSc2458 | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Probable isoleucyl-trna synthetase protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.804 |
| alaS | leuS | RSc0797 | RSc2744 | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Probable leucyl-trna synthetase (leucine--trna ligase) (leurs) protein; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.857 |
| alaS | pheS | RSc0797 | RSc1581 | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Probable phenylalanyl-trna synthetase alpha chain (phenylalanine--trna ligase alpha chain) (phers) protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.595 |
| alaS | pheT | RSc0797 | RSc1582 | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Probable phenylalanyl-trna synthetase beta chain (phenylalanine--trna ligase beta chain) (phers) protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.936 |
| alaS | purL | RSc0797 | RSc1722 | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.728 |
| alaS | rpoB | RSc0797 | RSc3034 | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.607 |
| alaS | thrS | RSc0797 | RSc1577 | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Probable threonyl-trna synthetase (threonine--trna ligase) protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.874 |
| alaS | tyrS | RSc0797 | RSc0496 | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | Probable tyrosyl-trna synthetase protein; Catalyzes the attachment of tyrosine to tRNA(Tyr) in a two- step reaction: tyrosine is first activated by ATP to form Tyr-AMP and then transferred to the acceptor end of tRNA(Tyr); Belongs to the class-I aminoacyl-tRNA synthetase family. TyrS type 2 subfamily. | 0.548 |
| guaA | alaS | RSc1431 | RSc0797 | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.703 |
| guaA | ileS | RSc1431 | RSc2458 | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | Probable isoleucyl-trna synthetase protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | 0.728 |
| guaA | leuS | RSc1431 | RSc2744 | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | Probable leucyl-trna synthetase (leucine--trna ligase) (leurs) protein; Belongs to the class-I aminoacyl-tRNA synthetase family. | 0.568 |
| guaA | pheS | RSc1431 | RSc1581 | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | Probable phenylalanyl-trna synthetase alpha chain (phenylalanine--trna ligase alpha chain) (phers) protein; Belongs to the class-II aminoacyl-tRNA synthetase family. Phe-tRNA synthetase alpha subunit type 1 subfamily. | 0.552 |
| guaA | pheT | RSc1431 | RSc1582 | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | Probable phenylalanyl-trna synthetase beta chain (phenylalanine--trna ligase beta chain) (phers) protein; Belongs to the phenylalanyl-tRNA synthetase beta subunit family. Type 1 subfamily. | 0.876 |
| guaA | purL | RSc1431 | RSc1722 | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate. | 0.983 |
| guaA | pyrD | RSc1431 | RSc1619 | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | Probable dihydroorotate dehydrogenase oxidoreductase protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily. | 0.717 |
| guaA | rpoB | RSc1431 | RSc3034 | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.935 |
| guaA | thrS | RSc1431 | RSc1577 | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | Probable threonyl-trna synthetase (threonine--trna ligase) protein; Catalyzes the attachment of threonine to tRNA(Thr) in a two- step reaction: L-threonine is first activated by ATP to form Thr-AMP and then transferred to the acceptor end of tRNA(Thr). Also edits incorrectly charged L-seryl-tRNA(Thr). | 0.574 |
| ileS | alaS | RSc2458 | RSc0797 | Probable isoleucyl-trna synthetase protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Probable alanyl-trna synthetase (alanine--trna ligase) (alars) protein; Catalyzes the attachment of alanine to tRNA(Ala) in a two- step reaction: alanine is first activated by ATP to form Ala-AMP and then transferred to the acceptor end of tRNA(Ala). Also edits incorrectly charged Ser-tRNA(Ala) and Gly-tRNA(Ala) via its editing domain. | 0.804 |
| ileS | guaA | RSc2458 | RSc1431 | Probable isoleucyl-trna synthetase protein; Catalyzes the attachment of isoleucine to tRNA(Ile). As IleRS can inadvertently accommodate and process structurally similar amino acids such as valine, to avoid such errors it has two additional distinct tRNA(Ile)-dependent editing activities. One activity is designated as 'pretransfer' editing and involves the hydrolysis of activated Val-AMP. The other activity is designated 'posttransfer' editing and involves deacylation of mischarged Val-tRNA(Ile). Belongs to the class-I aminoacyl-tRNA synthetase family. IleS type 1 subfamily. | Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP. | 0.728 |