| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0948 | cysE1 | RSc0948 | RSp1439 | Putative amino-acid dehydratase protein. | Probable serine acetyltransferase protein. | 0.808 |
| RSc0948 | glyA1 | RSc0948 | RSc0729 | Putative amino-acid dehydratase protein. | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
| RSc0948 | glyA2 | RSc0948 | RSp0055 | Putative amino-acid dehydratase protein. | Probable serine hydroxymethyltransferase 2 (serine methylase 2)(shmt 2) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
| RSc0948 | ilvA | RSc0948 | RSc0449 | Putative amino-acid dehydratase protein. | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 0.926 |
| RSc0948 | sda2b | RSc0948 | RSc1100 | Putative amino-acid dehydratase protein. | Probable inactivated l-serine amonya-lyase, l-serine dehydratase 2 (l-serine deaminase 2) protein. | 0.914 |
| RSc0948 | sdaA1 | RSc0948 | RSp0045 | Putative amino-acid dehydratase protein. | Probable l-serine dehydratase (l-serine deaminase) protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.914 |
| RSc0948 | sdaA2 | RSc0948 | RSc3296 | Putative amino-acid dehydratase protein. | Probable l-serine amonya-lyase, l-serine dehydratase 2 (l-serine deaminase) protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.914 |
| RSc0948 | serB | RSc0948 | RSc1640 | Putative amino-acid dehydratase protein. | Putative phosphoserine phosphatase protein. | 0.905 |
| RSc0948 | trpB | RSc0948 | RSc1983 | Putative amino-acid dehydratase protein. | Probable tryptophan synthase beta chain protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.928 |
| cysE1 | RSc0948 | RSp1439 | RSc0948 | Probable serine acetyltransferase protein. | Putative amino-acid dehydratase protein. | 0.808 |
| cysE1 | glyA1 | RSp1439 | RSc0729 | Probable serine acetyltransferase protein. | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.821 |
| cysE1 | glyA2 | RSp1439 | RSp0055 | Probable serine acetyltransferase protein. | Probable serine hydroxymethyltransferase 2 (serine methylase 2)(shmt 2) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.821 |
| cysE1 | ilvA | RSp1439 | RSc0449 | Probable serine acetyltransferase protein. | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 0.808 |
| cysE1 | sda2b | RSp1439 | RSc1100 | Probable serine acetyltransferase protein. | Probable inactivated l-serine amonya-lyase, l-serine dehydratase 2 (l-serine deaminase 2) protein. | 0.905 |
| cysE1 | sdaA1 | RSp1439 | RSp0045 | Probable serine acetyltransferase protein. | Probable l-serine dehydratase (l-serine deaminase) protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.905 |
| cysE1 | sdaA2 | RSp1439 | RSc3296 | Probable serine acetyltransferase protein. | Probable l-serine amonya-lyase, l-serine dehydratase 2 (l-serine deaminase) protein; Belongs to the iron-sulfur dependent L-serine dehydratase family. | 0.905 |
| cysE1 | serB | RSp1439 | RSc1640 | Probable serine acetyltransferase protein. | Putative phosphoserine phosphatase protein. | 0.955 |
| cysE1 | trpB | RSp1439 | RSc1983 | Probable serine acetyltransferase protein. | Probable tryptophan synthase beta chain protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.811 |
| glyA1 | RSc0948 | RSc0729 | RSc0948 | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative amino-acid dehydratase protein. | 0.909 |
| glyA1 | cysE1 | RSc0729 | RSp1439 | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Probable serine acetyltransferase protein. | 0.821 |