STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pdhAProbable pyruvate dehydrogenase e1 component (alpha subunit) oxidoreductase protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3). (363 aa)    
Predicted Functional Partners:
lpdA
Probable dihydrolipoamide dehydrogenase (e3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) protein.
 0.999
RSc1798
Putative pyruvate decarboxylase e1 (beta subunit) oxidoreductase protein.
 0.999
RSc1799
Putative dihydrolipoamide acetyltransferase (component e2 of pyruvate dehydrogenase complex) protein.
 
 0.999
aceF
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 
 0.997
RSc1271
Probable dihydrolipoamide dehydrogenase (component of pyruvate and 2-oxoglutarate dehydrogenases complexes) oxidoreductase protein.
 
 0.990
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 
 0.976
maeB1
Putative nadp-dependent malic enzyme oxidoreductase protein.
  
 
 0.968
maeB2
Putative nadp-dependent malic enzyme oxidoreductase protein.
  
 
 0.968
ppsA
Probable phosphoenolpyruvate synthase protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.924
aceE
Probable pyruvate dehydrogenase e1 component oxidoreductase protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
    
 0.923
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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