STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
RSc1798Putative pyruvate decarboxylase e1 (beta subunit) oxidoreductase protein. (326 aa)    
Predicted Functional Partners:
lpdA
Probable dihydrolipoamide dehydrogenase (e3 component of pyruvate and 2-oxoglutarate dehydrogenases complexes) protein.
 
 0.999
pdhA
Probable pyruvate dehydrogenase e1 component (alpha subunit) oxidoreductase protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
 0.999
RSc1799
Putative dihydrolipoamide acetyltransferase (component e2 of pyruvate dehydrogenase complex) protein.
 0.999
RSc1271
Probable dihydrolipoamide dehydrogenase (component of pyruvate and 2-oxoglutarate dehydrogenases complexes) oxidoreductase protein.
 0.996
sucB
Dihydrolipoyllysine-residue succinyltransferase component of 2-oxoglutarate dehydrogenase complex; E2 component of the 2-oxoglutarate dehydrogenase (OGDH) complex which catalyzes the second step in the conversion of 2- oxoglutarate to succinyl-CoA and CO(2).
 0.988
aceF
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
 0.984
gor
Probable glutathione reductase oxidoreductase protein.
 
 0.963
RSp1380
Putative pyruvate/2-oxoglutarate dehydrogenase complex, dihydrolipoamide dehydrogenase (e3) component, and related enzymes oxidoreductase protein.
 
 0.946
ilvE
Probable branched-chain amino acid aminotransferase protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
   
 0.923
ilvE3
Probable branched-chain amino acid aminotransferase protein.
   
 0.923
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: low (22%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.