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STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
fumAProbable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. (507 aa)    
Predicted Functional Partners:
sdhA
Putative succinate dehydrogenase (flavoprotein subunit) oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.997
mdh
Probable malate dehydrogenase. oxidoreductase protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 
 0.997
sdhB
Putative succinate dehydrogenase (iron-sulfur subunit) oxidoreductase protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
 
 0.992
fumC
Probable fumarate hydratase class II (fumarase c) protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.992
sdhD
Putative transmembrane succinate dehydrogenase (hydrophobic membrane anchor subunit) oxidoreductase protein.
  
 
 0.981
gltA
Probable citrate synthase protein; Belongs to the citrate synthase family.
  
 
 0.976
sdhC
Putative transmembrane succinate dehydrogenase (cytochrome b-556 subunit) oxidoreductase protein.
  
 
 0.975
icd
Probable isocitrate dehydrogenase [nadp] oxidoreductase protein.
  
  
 0.972
maeB1
Putative nadp-dependent malic enzyme oxidoreductase protein.
 
 
 0.965
maeB2
Putative nadp-dependent malic enzyme oxidoreductase protein.
 
 
 0.965
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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