| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc1326 | fumA | RSc1326 | RSc1955 | Probable aspartate aminotransferase protein. | Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.811 |
| RSc1326 | gdhA | RSc1326 | RSc0480 | Probable aspartate aminotransferase protein. | Probable glutamate dehydrogenase (nad(p)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.907 |
| RSc1326 | gltB | RSc1326 | RSc2965 | Probable aspartate aminotransferase protein. | Probable glutamate synthase (large subunit) oxidoreductase protein. | 0.543 |
| RSc1326 | murI | RSc1326 | RSc1956 | Probable aspartate aminotransferase protein. | Probable glutamate racemase protein; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.814 |
| RSc2160 | fumA | RSc2160 | RSc1955 | Putative xanthosine triphosphate pyrophosphatase protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.425 |
| RSc2160 | murI | RSc2160 | RSc1956 | Putative xanthosine triphosphate pyrophosphatase protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | Probable glutamate racemase protein; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.915 |
| fumA | RSc1326 | RSc1955 | RSc1326 | Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Probable aspartate aminotransferase protein. | 0.811 |
| fumA | RSc2160 | RSc1955 | RSc2160 | Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Putative xanthosine triphosphate pyrophosphatase protein; Pyrophosphatase that catalyzes the hydrolysis of nucleoside triphosphates to their monophosphate derivatives, with a high preference for the non-canonical purine nucleotides XTP (xanthosine triphosphate), dITP (deoxyinosine triphosphate) and ITP. Seems to function as a house-cleaning enzyme that removes non-canonical purine nucleotides from the nucleotide pool, thus preventing their incorporation into DNA/RNA and avoiding chromosomal lesions. Belongs to the HAM1 NTPase family. | 0.425 |
| fumA | gdhA | RSc1955 | RSc0480 | Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Probable glutamate dehydrogenase (nad(p)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.449 |
| fumA | gltB | RSc1955 | RSc2965 | Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Probable glutamate synthase (large subunit) oxidoreductase protein. | 0.410 |
| fumA | murI | RSc1955 | RSc1956 | Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | Probable glutamate racemase protein; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.813 |
| gdhA | RSc1326 | RSc0480 | RSc1326 | Probable glutamate dehydrogenase (nad(p)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Probable aspartate aminotransferase protein. | 0.907 |
| gdhA | fumA | RSc0480 | RSc1955 | Probable glutamate dehydrogenase (nad(p)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family. | 0.449 |
| gdhA | glnA2 | RSc0480 | RSp0886 | Probable glutamate dehydrogenase (nad(p)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Probable glutamine synthetase protein. | 0.945 |
| gdhA | glsA | RSc0480 | RSp1143 | Probable glutamate dehydrogenase (nad(p)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Probable glutaminase protein; Belongs to the glutaminase family. | 0.916 |
| gdhA | gltB | RSc0480 | RSc2965 | Probable glutamate dehydrogenase (nad(p)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Probable glutamate synthase (large subunit) oxidoreductase protein. | 0.987 |
| gdhA | murI | RSc0480 | RSc1956 | Probable glutamate dehydrogenase (nad(p)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Probable glutamate racemase protein; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.858 |
| gdhA | putA | RSc0480 | RSc3301 | Probable glutamate dehydrogenase (nad(p)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | Delta-1-pyrroline-5-carboxylate dehydrogenase; Oxidizes proline to glutamate for use as a carbon and nitrogen source; In the C-terminal section; belongs to the aldehyde dehydrogenase family. | 0.968 |
| glnA2 | gdhA | RSp0886 | RSc0480 | Probable glutamine synthetase protein. | Probable glutamate dehydrogenase (nad(p)+) oxidoreductase protein; Belongs to the Glu/Leu/Phe/Val dehydrogenases family. | 0.945 |
| glnA2 | glsA | RSp0886 | RSp1143 | Probable glutamine synthetase protein. | Probable glutaminase protein; Belongs to the glutaminase family. | 0.918 |