| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0948 | ilvA | RSc0948 | RSc0449 | Putative amino-acid dehydratase protein. | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 0.926 |
| RSc0948 | ilvG | RSc0948 | RSc1353 | Putative amino-acid dehydratase protein. | Putative acetolactate synthase isozyme II (large subunit) protein; Belongs to the TPP enzyme family. | 0.942 |
| RSc0948 | ilvH | RSc0948 | RSc2076 | Putative amino-acid dehydratase protein. | Probable acetolactate synthase isozyme III (small subunit) protein. | 0.942 |
| RSc0948 | ilvI | RSc0948 | RSc2077 | Putative amino-acid dehydratase protein. | Probable acetolactate synthase isozyme III (large subunit) protein. | 0.934 |
| RSc0948 | leuB1 | RSc0948 | RSc1988 | Putative amino-acid dehydratase protein. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.936 |
| RSc0948 | leuB2 | RSc0948 | RSp0329 | Putative amino-acid dehydratase protein. | Probable 3-isopropylmalate dehydrogenase oxidoreductase protein. | 0.933 |
| RSp1233 | leuB1 | RSp1233 | RSc1988 | Putative dimethylmenaquinone methyltransferase; protein. | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.866 |
| ilvA | RSc0948 | RSc0449 | RSc0948 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Putative amino-acid dehydratase protein. | 0.926 |
| ilvA | ilvG | RSc0449 | RSc1353 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Putative acetolactate synthase isozyme II (large subunit) protein; Belongs to the TPP enzyme family. | 0.934 |
| ilvA | ilvH | RSc0449 | RSc2076 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Probable acetolactate synthase isozyme III (small subunit) protein. | 0.951 |
| ilvA | ilvI | RSc0449 | RSc2077 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Probable acetolactate synthase isozyme III (large subunit) protein. | 0.944 |
| ilvA | leuB1 | RSc0449 | RSc1988 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 3-isopropylmalate dehydrogenase; Catalyzes the oxidation of 3-carboxy-2-hydroxy-4- methylpentanoate (3-isopropylmalate) to 3-carboxy-4-methyl-2- oxopentanoate. The product decarboxylates to 4-methyl-2 oxopentanoate. Belongs to the isocitrate and isopropylmalate dehydrogenases family. LeuB type 1 subfamily. | 0.942 |
| ilvA | leuB2 | RSc0449 | RSp0329 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Probable 3-isopropylmalate dehydrogenase oxidoreductase protein. | 0.924 |
| ilvA | leuC | RSc0449 | RSc1990 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 3-isopropylmalate dehydratase large subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. | 0.458 |
| ilvA | leuD | RSc0449 | RSc1989 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 3-isopropylmalate dehydratase small subunit; Catalyzes the isomerization between 2-isopropylmalate and 3- isopropylmalate, via the formation of 2-isopropylmaleate. Belongs to the LeuD family. LeuD type 1 subfamily. | 0.478 |
| ilvG | RSc0948 | RSc1353 | RSc0948 | Putative acetolactate synthase isozyme II (large subunit) protein; Belongs to the TPP enzyme family. | Putative amino-acid dehydratase protein. | 0.942 |
| ilvG | ilvA | RSc1353 | RSc0449 | Putative acetolactate synthase isozyme II (large subunit) protein; Belongs to the TPP enzyme family. | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 0.934 |
| ilvG | ilvH | RSc1353 | RSc2076 | Putative acetolactate synthase isozyme II (large subunit) protein; Belongs to the TPP enzyme family. | Probable acetolactate synthase isozyme III (small subunit) protein. | 0.996 |
| ilvG | ilvI | RSc1353 | RSc2077 | Putative acetolactate synthase isozyme II (large subunit) protein; Belongs to the TPP enzyme family. | Probable acetolactate synthase isozyme III (large subunit) protein. | 0.925 |
| ilvG | leuA1 | RSc1353 | RSc2072 | Putative acetolactate synthase isozyme II (large subunit) protein; Belongs to the TPP enzyme family. | 2-isopropylmalate synthase 1; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily. | 0.922 |
