STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
gltAProbable citrate synthase protein; Belongs to the citrate synthase family. (433 aa)    
Predicted Functional Partners:
mdh
Probable malate dehydrogenase. oxidoreductase protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.988
acnA1
Probable aconitate hydratase protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.983
acnA3
Probable aconitate hydratase 1 protein; Catalyzes the isomerization of citrate to isocitrate via cis- aconitate.
 
 0.982
fumA
Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
  
 
 0.976
mqo
Probable malate:quinone oxidoreductase (malatedehydrogenase [acceptor]) (mqo). oxidoreductase protein.
  
 
 0.974
acnB
Probable aconitate hydratase 2 transmembrane protein; Belongs to the aconitase/IPM isomerase family.
  
 
 0.971
aceB
Probable malate synthase a (msa or masy protein); Belongs to the malate synthase family.
   
 0.970
aceF
Acetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 0.955
RSc1799
Putative dihydrolipoamide acetyltransferase (component e2 of pyruvate dehydrogenase complex) protein.
  
 0.955
acsA
Probable acetyl-coenzyme a synthetase (acetate--coa ligase) (acyl-activating enzyme) protein; Catalyzes the conversion of acetate into acetyl-CoA (AcCoA), an essential intermediate at the junction of anabolic and catabolic pathways. AcsA undergoes a two-step reaction. In the first half reaction, AcsA combines acetate with ATP to form acetyl-adenylate (AcAMP) intermediate. In the second half reaction, it can then transfer the acetyl group from AcAMP to the sulfhydryl group of CoA, forming the product AcCoA; Belongs to the ATP-dependent AMP-binding enzyme family.
  
 0.948
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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