STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
sdhEConserved hypothetical protein; An FAD assembly protein, which accelerates covalent attachment of the cofactor into other proteins. Plays an essential role in the assembly of succinate dehydrogenase (SDH, respiratory complex II), an enzyme complex that is a component of both the tricarboxylic acid cycle and the electron transport chain, and which couples the oxidation of succinate to fumarate with the reduction of ubiquinone (coenzyme Q) to ubiquinol. Required for flavinylation (covalent attachment of FAD) of the flavoprotein subunit SdhA of SDH and other flavinylated proteins as well. (95 aa)    
Predicted Functional Partners:
sdhA
Putative succinate dehydrogenase (flavoprotein subunit) oxidoreductase; Belongs to the FAD-dependent oxidoreductase 2 family. FRD/SDH subfamily.
  
 
 0.970
sdhC
Putative transmembrane succinate dehydrogenase (cytochrome b-556 subunit) oxidoreductase protein.
 
   
 0.839
sdhD
Putative transmembrane succinate dehydrogenase (hydrophobic membrane anchor subunit) oxidoreductase protein.
 
     0.791
sdhB
Putative succinate dehydrogenase (iron-sulfur subunit) oxidoreductase protein; Belongs to the succinate dehydrogenase/fumarate reductase iron-sulfur protein family.
  
  
 0.786
priB
Probable primosomal replication protein n; Binds single-stranded DNA at the primosome assembly site (PAS); Belongs to the PriB family.
  
     0.763
RSc1181
Probable cog1807, 4-amino-4-deoxy-l-arabinose transferase and related glycosyltransferases of pmt family transmembrane protein.
  
     0.741
RSc2385
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
  
     0.739
RSc0562
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
  
     0.701
RSc1227
Putative nucleotide phosphoribosyltransferase protein.
  
     0.701
RSc0709
Putative transglycosylase transmembrane protein.
  
     0.686
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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