| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0948 | glyA1 | RSc0948 | RSc0729 | Putative amino-acid dehydratase protein. | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
| RSc0948 | ilvA | RSc0948 | RSc0449 | Putative amino-acid dehydratase protein. | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 0.926 |
| RSc0948 | pssA | RSc0948 | RSc2073 | Putative amino-acid dehydratase protein. | Putative cdp-diacylglycerol--serine o-phosphatidyltransferase protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| RSc0948 | sda2b | RSc0948 | RSc1100 | Putative amino-acid dehydratase protein. | Probable inactivated l-serine amonya-lyase, l-serine dehydratase 2 (l-serine deaminase 2) protein. | 0.914 |
| RSc0948 | serB | RSc0948 | RSc1640 | Putative amino-acid dehydratase protein. | Putative phosphoserine phosphatase protein. | 0.905 |
| RSc0948 | trpA | RSc0948 | RSc1981 | Putative amino-acid dehydratase protein. | Probable tryptophan synthase alpha chain protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.920 |
| RSc0948 | trpB | RSc0948 | RSc1983 | Putative amino-acid dehydratase protein. | Probable tryptophan synthase beta chain protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.928 |
| cdsA | pgsA | RSc1409 | RSc1072 | Probable phosphatidate cytidylyltransferase transmembrane protein; Belongs to the CDS family. | Probable cdp-diacylglycerol--glycerol-3-phosphate 3-phosphatidyltransferase transmembrane protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.958 |
| cdsA | psd | RSc1409 | RSc2074 | Probable phosphatidate cytidylyltransferase transmembrane protein; Belongs to the CDS family. | Phosphatidylserine decarboxylase alpha chain; Catalyzes the formation of phosphatidylethanolamine (PtdEtn) from phosphatidylserine (PtdSer). | 0.738 |
| cdsA | pssA | RSc1409 | RSc2073 | Probable phosphatidate cytidylyltransferase transmembrane protein; Belongs to the CDS family. | Putative cdp-diacylglycerol--serine o-phosphatidyltransferase protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.927 |
| glyA1 | RSc0948 | RSc0729 | RSc0948 | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative amino-acid dehydratase protein. | 0.909 |
| glyA1 | ilvA | RSc0729 | RSc0449 | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | 0.909 |
| glyA1 | pssA | RSc0729 | RSc2073 | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative cdp-diacylglycerol--serine o-phosphatidyltransferase protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |
| glyA1 | sda2b | RSc0729 | RSc1100 | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Probable inactivated l-serine amonya-lyase, l-serine dehydratase 2 (l-serine deaminase 2) protein. | 0.934 |
| glyA1 | serB | RSc0729 | RSc1640 | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Putative phosphoserine phosphatase protein. | 0.922 |
| glyA1 | trpA | RSc0729 | RSc1981 | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Probable tryptophan synthase alpha chain protein; The alpha subunit is responsible for the aldol cleavage of indoleglycerol phosphate to indole and glyceraldehyde 3-phosphate. Belongs to the TrpA family. | 0.923 |
| glyA1 | trpB | RSc0729 | RSc1983 | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | Probable tryptophan synthase beta chain protein; The beta subunit is responsible for the synthesis of L- tryptophan from indole and L-serine. | 0.917 |
| ilvA | RSc0948 | RSc0449 | RSc0948 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Putative amino-acid dehydratase protein. | 0.926 |
| ilvA | glyA1 | RSc0449 | RSc0729 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Probable serine hydroxymethyltransferase 1 (serine methylase 1)(shmt 1) protein; Catalyzes the reversible interconversion of serine and glycine with tetrahydrofolate (THF) serving as the one-carbon carrier. This reaction serves as the major source of one-carbon groups required for the biosynthesis of purines, thymidylate, methionine, and other important biomolecules. Also exhibits THF-independent aldolase activity toward beta-hydroxyamino acids, producing glycine and aldehydes, via a retro-aldol mechanism. | 0.909 |
| ilvA | pssA | RSc0449 | RSc2073 | Probable threonine amonia-lyase (threonine dehydratase, threonine deaminase) transmembrane protein; Catalyzes the anaerobic formation of alpha-ketobutyrate and ammonia from threonine in a two-step reaction. The first step involved a dehydration of threonine and a production of enamine intermediates (aminocrotonate), which tautomerizes to its imine form (iminobutyrate). Both intermediates are unstable and short-lived. The second step is the nonenzymatic hydrolysis of the enamine/imine intermediates to form 2- ketobutyrate and free ammonia. In the low water environment of the cell, the s [...] | Putative cdp-diacylglycerol--serine o-phosphatidyltransferase protein; Belongs to the CDP-alcohol phosphatidyltransferase class-I family. | 0.900 |