STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
guaDProbable guanine deaminase (guanine aminohydrolase) (gah) protein; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (445 aa)    
Predicted Functional Partners:
xdhB
Probable xanthine dehydrogenase (subunit b) oxidoreductase protein.
 
 
 0.991
xdhA
Putative xanthine dehydrogenase (subunit a) oxidoreductase protein.
 
  
  0.986
xdhC
Probable xanthine dehydrogenase protein.
 
 
  0.962
hprT
Probable hypoxanthine phosphoribosyltransferase transmembrane protein.
 
  
 0.930
apt
Probable adenine phosphoribosyltransferase (aprt) protein; Catalyzes a salvage reaction resulting in the formation of AMP, that is energically less costly than de novo synthesis.
     
 0.910
RSc2548
Putative inosine-uridine preferring nucleoside hydrolase transmembrane protein.
  
 
 0.907
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
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Probable adenosine deaminase (adenosine aminohydrolase) protein; Catalyzes the hydrolytic deamination of adenine to hypoxanthine. Plays an important role in the purine salvage pathway and in nitrogen catabolism.
 
 
 
 0.805
RSc2116
Hypothetical transthyretin-like protein; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily.
 
   
 0.794
RSc2121
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
 
     0.766
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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