STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
maeB1Putative nadp-dependent malic enzyme oxidoreductase protein. (773 aa)    
Predicted Functional Partners:
aceB
Probable malate synthase a (msa or masy protein); Belongs to the malate synthase family.
  
 
 0.980
RSc1798
Putative pyruvate decarboxylase e1 (beta subunit) oxidoreductase protein.
  
 
 0.973
fumC
Probable fumarate hydratase class II (fumarase c) protein; Involved in the TCA cycle. Catalyzes the stereospecific interconversion of fumarate to L-malate; Belongs to the class-II fumarase/aspartase family. Fumarase subfamily.
  
 
 0.969
pdhA
Probable pyruvate dehydrogenase e1 component (alpha subunit) oxidoreductase protein; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). It contains multiple copies of three enzymatic components: pyruvate dehydrogenase (E1), dihydrolipoamide acetyltransferase (E2) and lipoamide dehydrogenase (E3).
  
 
 0.968
mdh
Probable malate dehydrogenase. oxidoreductase protein; Catalyzes the reversible oxidation of malate to oxaloacetate. Belongs to the LDH/MDH superfamily. MDH type 2 family.
  
 0.967
fumA
Probable fumarate hydratase protein; Catalyzes the reversible hydration of fumarate to (S)-malate. Belongs to the class-I fumarase family.
 
 
 0.965
pykA1
Probable pyruvate kinase II protein; Belongs to the pyruvate kinase family.
  
 0.963
pykA2
Probable pyruvate kinase II protein; Belongs to the pyruvate kinase family.
  
 0.963
aceE
Probable pyruvate dehydrogenase e1 component oxidoreductase protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
  
 
 0.951
mqo
Probable malate:quinone oxidoreductase (malatedehydrogenase [acceptor]) (mqo). oxidoreductase protein.
  
 
 0.948
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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