STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
uppProbable uracil phosphoribosyltransferase (ump pyrophosphorylase)(uprtase) protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. (216 aa)    
Predicted Functional Partners:
pyrH
Probable uridylate kinase (uk) (uridine monophosphate kinase) (umpkinase) protein; Catalyzes the reversible phosphorylation of UMP to UDP.
  
 
 0.968
codA
Probable cytosine deaminase (cytosine aminohydrolase) protein.
  
 
 0.963
deoA
Putative thymidine phosphorylase (tdrpase) protein.
    
 0.943
pyrF
Probable orotidine 5'-phosphate decarboxylase (omp decarboxylase)(ompdcase) (ompdecase) protein; Belongs to the OMP decarboxylase family. Type 2 subfamily.
  
 
 0.940
pyrR
Putative pyrr bifunctional protein [includes: pyrimidine operon regulatoryprotein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.
     
 0.917
surE
Probable 5'-nucleotidase sure (nucleoside 5'-monophosphatephosphohydrolase) protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
     
 0.916
RSc2196
Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids.
    
  0.900
ppnP
Conserved hypothetical protein; Catalyzes the phosphorolysis of diverse nucleosides, yielding D-ribose 1-phosphate and the respective free bases. Can use uridine, adenosine, guanosine, cytidine, thymidine, inosine and xanthosine as substrates. Also catalyzes the reverse reactions.
     
  0.900
pyrB
Probable aspartate carbamoyltransferase (aspartatetranscarbamylase) (atcase) protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
   
  
 0.774
pyrD
Probable dihydroorotate dehydrogenase oxidoreductase protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
   
  
 0.702
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: medium (42%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.