| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc2196 | cmk | RSc2196 | RSc0908 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Probable cytidylate kinase (ck) (cytidine monophosphate kinase)(cmp kinase) protein. | 0.906 |
| RSc2196 | ndk | RSc2196 | RSc1211 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Probable nucleoside diphosphate kinase (ndk) (ndp kinase)(nucleoside-2-p kinase) protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.906 |
| RSc2196 | pyrF | RSc2196 | RSc2773 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Probable orotidine 5'-phosphate decarboxylase (omp decarboxylase)(ompdcase) (ompdecase) protein; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.900 |
| RSc2196 | pyrG | RSc2196 | RSc1126 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Probable ctp synthase (utp--ammonia ligase) (ctp synthetase) protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.908 |
| RSc2196 | pyrH | RSc2196 | RSc1406 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Probable uridylate kinase (uk) (uridine monophosphate kinase) (umpkinase) protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.900 |
| RSc2196 | pyrR | RSc2196 | RSc0677 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Putative pyrr bifunctional protein [includes: pyrimidine operon regulatoryprotein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines. | 0.902 |
| RSc2196 | surE | RSc2196 | RSc1204 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Probable 5'-nucleotidase sure (nucleoside 5'-monophosphatephosphohydrolase) protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.900 |
| RSc2196 | thyA | RSc2196 | RSc0947 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Probable thymidylate synthase (ts) (tsase) protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.900 |
| RSc2196 | tmk | RSc2196 | RSc1784 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Probable thymidylate kinase (dtmp kinase) protein; Phosphorylation of dTMP to form dTDP in both de novo and salvage pathways of dTTP synthesis; Belongs to the thymidylate kinase family. | 0.905 |
| RSc2196 | upp | RSc2196 | RSc2188 | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | Probable uracil phosphoribosyltransferase (ump pyrophosphorylase)(uprtase) protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate. | 0.900 |
| cmk | RSc2196 | RSc0908 | RSc2196 | Probable cytidylate kinase (ck) (cytidine monophosphate kinase)(cmp kinase) protein. | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.906 |
| cmk | ndk | RSc0908 | RSc1211 | Probable cytidylate kinase (ck) (cytidine monophosphate kinase)(cmp kinase) protein. | Probable nucleoside diphosphate kinase (ndk) (ndp kinase)(nucleoside-2-p kinase) protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | 0.933 |
| cmk | pyrF | RSc0908 | RSc2773 | Probable cytidylate kinase (ck) (cytidine monophosphate kinase)(cmp kinase) protein. | Probable orotidine 5'-phosphate decarboxylase (omp decarboxylase)(ompdcase) (ompdecase) protein; Belongs to the OMP decarboxylase family. Type 2 subfamily. | 0.424 |
| cmk | pyrG | RSc0908 | RSc1126 | Probable cytidylate kinase (ck) (cytidine monophosphate kinase)(cmp kinase) protein. | Probable ctp synthase (utp--ammonia ligase) (ctp synthetase) protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.704 |
| cmk | pyrH | RSc0908 | RSc1406 | Probable cytidylate kinase (ck) (cytidine monophosphate kinase)(cmp kinase) protein. | Probable uridylate kinase (uk) (uridine monophosphate kinase) (umpkinase) protein; Catalyzes the reversible phosphorylation of UMP to UDP. | 0.798 |
| cmk | surE | RSc0908 | RSc1204 | Probable cytidylate kinase (ck) (cytidine monophosphate kinase)(cmp kinase) protein. | Probable 5'-nucleotidase sure (nucleoside 5'-monophosphatephosphohydrolase) protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family. | 0.928 |
| cmk | thyA | RSc0908 | RSc0947 | Probable cytidylate kinase (ck) (cytidine monophosphate kinase)(cmp kinase) protein. | Probable thymidylate synthase (ts) (tsase) protein; Catalyzes the reductive methylation of 2'-deoxyuridine-5'- monophosphate (dUMP) to 2'-deoxythymidine-5'-monophosphate (dTMP) while utilizing 5,10-methylenetetrahydrofolate (mTHF) as the methyl donor and reductant in the reaction, yielding dihydrofolate (DHF) as a by- product. This enzymatic reaction provides an intracellular de novo source of dTMP, an essential precursor for DNA biosynthesis. | 0.638 |
| ndk | RSc2196 | RSc1211 | RSc2196 | Probable nucleoside diphosphate kinase (ndk) (ndp kinase)(nucleoside-2-p kinase) protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Putative nucleotide-binding protein implicated in inhibition of septum formation; Nucleoside triphosphate pyrophosphatase that hydrolyzes dTTP and UTP. May have a dual role in cell division arrest and in preventing the incorporation of modified nucleotides into cellular nucleic acids. | 0.906 |
| ndk | cmk | RSc1211 | RSc0908 | Probable nucleoside diphosphate kinase (ndk) (ndp kinase)(nucleoside-2-p kinase) protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Probable cytidylate kinase (ck) (cytidine monophosphate kinase)(cmp kinase) protein. | 0.933 |
| ndk | pyrG | RSc1211 | RSc1126 | Probable nucleoside diphosphate kinase (ndk) (ndp kinase)(nucleoside-2-p kinase) protein; Major role in the synthesis of nucleoside triphosphates other than ATP. The ATP gamma phosphate is transferred to the NDP beta phosphate via a ping-pong mechanism, using a phosphorylated active-site intermediate; Belongs to the NDK family. | Probable ctp synthase (utp--ammonia ligase) (ctp synthetase) protein; Catalyzes the ATP-dependent amination of UTP to CTP with either L-glutamine or ammonia as the source of nitrogen. Regulates intracellular CTP levels through interactions with the four ribonucleotide triphosphates. | 0.942 |
