STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
waaLProbable lipopolysaccharide o-antigen ligase transmembrane protein. (435 aa)    
Predicted Functional Partners:
rfaF
Probable adp-heptose--lipopolysaccharide heptosyltransferase II protein.
  
 
 0.934
RSc2201
Putative glycosyl transferase, family 2; signal peptide protein.
 
  
 0.933
kdtA
Probable 3-deoxy-d-manno-octulosonic-acid transferase transmembrane protein; Involved in lipopolysaccharide (LPS) biosynthesis. Catalyzes the transfer of 3-deoxy-D-manno-octulosonate (Kdo) residue(s) from CMP- Kdo to lipid IV(A), the tetraacyldisaccharide-1,4'-bisphosphate precursor of lipid A; Belongs to the glycosyltransferase group 1 family.
    
 0.922
rfaC1
Probable lipopolysaccharide heptosyltransferase protein.
  
 
 0.920
rfaC2
Probable lipopolysaccharide heptosyltransferase protein.
  
 
 0.920
RSc2203
Putative glycosyl transferase, family 2;peptidase m protein.
 
  
 0.897
kdsB
Probable 3-deoxy-manno-octulosonate (cmp-kdo synthetase)(cks) protein; Activates KDO (a required 8-carbon sugar) for incorporation into bacterial lipopolysaccharide in Gram-negative bacteria.
     
 0.613
lapB
Hypothetical transmembrane protein; Modulates cellular lipopolysaccharide (LPS) levels by regulating LpxC, which is involved in lipid A biosynthesis. May act by modulating the proteolytic activity of FtsH towards LpxC. May also coordinate assembly of proteins involved in LPS synthesis at the plasma membrane; Belongs to the LapB family.
      
 0.594
epsB
Putative tyrosine-protein kinase epsb (eps ipolysaccharide export epsb). transmembrane; Probably involved in polymerization and/or export of exopolysaccharide EPS I which functions as a virulence factor. May be involved in an ATP-dependent process in the pathway for EPS I production, possibly export of the trimeric repeat units across the inner membrane or their polymerization (By similarity).
  
  
 0.582
lpxK
Probable tetraacyldisaccharide 4'-kinase (lipid a 4'-kinase) protein; Transfers the gamma-phosphate of ATP to the 4'-position of a tetraacyldisaccharide 1-phosphate intermediate (termed DS-1-P) to form tetraacyldisaccharide 1,4'-bis-phosphate (lipid IVA).
     
 0.540
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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