node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
dnaG | nusA | RSc2216 | RSc1288 | Probable dna primase protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Probable n utilization substance transcription regulator protein; Participates in both transcription termination and antitermination. | 0.421 |
dnaG | rpoA | RSc2216 | RSc2993 | Probable dna primase protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.561 |
dnaG | rpoB | RSc2216 | RSc3034 | Probable dna primase protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.604 |
dnaG | rpoD | RSc2216 | RSc2215 | Probable dna primase protein; RNA polymerase that catalyzes the synthesis of short RNA molecules used as primers for DNA polymerase during DNA replication. | Probable rna polymerase sigma d (sigma-70) factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.880 |
dnaK | efp | RSc2635 | RSc1069 | Probable chaperone protein dnak (heat shock protein 70) (heat shock 70 kdaprotein) (hsp70); Acts as a chaperone.; Belongs to the heat shock protein 70 family. | Probable elongation factor p (ef-p) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.702 |
dnaK | gyrB | RSc2635 | RSc3440 | Probable chaperone protein dnak (heat shock protein 70) (heat shock 70 kdaprotein) (hsp70); Acts as a chaperone.; Belongs to the heat shock protein 70 family. | Probable dna gyrase (subunit b) protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-depen [...] | 0.887 |
dnaK | lepA | RSc2635 | RSc1060 | Probable chaperone protein dnak (heat shock protein 70) (heat shock 70 kdaprotein) (hsp70); Acts as a chaperone.; Belongs to the heat shock protein 70 family. | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.602 |
dnaK | rpoB | RSc2635 | RSc3034 | Probable chaperone protein dnak (heat shock protein 70) (heat shock 70 kdaprotein) (hsp70); Acts as a chaperone.; Belongs to the heat shock protein 70 family. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.507 |
dnaK | rpoD | RSc2635 | RSc2215 | Probable chaperone protein dnak (heat shock protein 70) (heat shock 70 kdaprotein) (hsp70); Acts as a chaperone.; Belongs to the heat shock protein 70 family. | Probable rna polymerase sigma d (sigma-70) factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.775 |
efp | dnaK | RSc1069 | RSc2635 | Probable elongation factor p (ef-p) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Probable chaperone protein dnak (heat shock protein 70) (heat shock 70 kdaprotein) (hsp70); Acts as a chaperone.; Belongs to the heat shock protein 70 family. | 0.702 |
efp | gyrB | RSc1069 | RSc3440 | Probable elongation factor p (ef-p) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Probable dna gyrase (subunit b) protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-depen [...] | 0.614 |
efp | lepA | RSc1069 | RSc1060 | Probable elongation factor p (ef-p) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.773 |
efp | nusA | RSc1069 | RSc1288 | Probable elongation factor p (ef-p) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Probable n utilization substance transcription regulator protein; Participates in both transcription termination and antitermination. | 0.735 |
efp | rpoA | RSc1069 | RSc2993 | Probable elongation factor p (ef-p) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | DNA-directed RNA polymerase subunit alpha; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.681 |
efp | rpoB | RSc1069 | RSc3034 | Probable elongation factor p (ef-p) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | DNA-directed RNA polymerase subunit beta; DNA-dependent RNA polymerase catalyzes the transcription of DNA into RNA using the four ribonucleoside triphosphates as substrates. | 0.572 |
efp | rpoD | RSc1069 | RSc2215 | Probable elongation factor p (ef-p) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | Probable rna polymerase sigma d (sigma-70) factor transcription regulator protein; Sigma factors are initiation factors that promote the attachment of RNA polymerase to specific initiation sites and are then released. This sigma factor is the primary sigma factor during exponential growth. | 0.805 |
efp | rpoZ | RSc1069 | RSc2154 | Probable elongation factor p (ef-p) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | DNA-directed RNA polymerase subunit omega; Promotes RNA polymerase assembly. Latches the N- and C- terminal regions of the beta' subunit thereby facilitating its interaction with the beta and alpha subunits. | 0.674 |
gyrB | dnaK | RSc3440 | RSc2635 | Probable dna gyrase (subunit b) protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-depen [...] | Probable chaperone protein dnak (heat shock protein 70) (heat shock 70 kdaprotein) (hsp70); Acts as a chaperone.; Belongs to the heat shock protein 70 family. | 0.887 |
gyrB | efp | RSc3440 | RSc1069 | Probable dna gyrase (subunit b) protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-depen [...] | Probable elongation factor p (ef-p) protein; Involved in peptide bond synthesis. Stimulates efficient translation and peptide-bond synthesis on native or reconstituted 70S ribosomes in vitro. Probably functions indirectly by altering the affinity of the ribosome for aminoacyl-tRNA, thus increasing their reactivity as acceptors for peptidyl transferase. | 0.614 |
gyrB | lepA | RSc3440 | RSc1060 | Probable dna gyrase (subunit b) protein; A type II topoisomerase that negatively supercoils closed circular double-stranded (ds) DNA in an ATP-dependent manner to modulate DNA topology and maintain chromosomes in an underwound state. Negative supercoiling favors strand separation, and DNA replication, transcription, recombination and repair, all of which involve strand separation. Also able to catalyze the interconversion of other topological isomers of dsDNA rings, including catenanes and knotted rings. Type II topoisomerases break and join 2 DNA strands simultaneously in an ATP-depen [...] | Probable ggtp-binding protein lepa; Required for accurate and efficient protein synthesis under certain stress conditions. May act as a fidelity factor of the translation reaction, by catalyzing a one-codon backward translocation of tRNAs on improperly translocated ribosomes. Back-translocation proceeds from a post-translocation (POST) complex to a pre- translocation (PRE) complex, thus giving elongation factor G a second chance to translocate the tRNAs correctly. Binds to ribosomes in a GTP- dependent manner. | 0.749 |