STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pcaBProbable 3-carboxy-cis,cis-muconate cycloisomerase protein. (453 aa)    
Predicted Functional Partners:
pcaC
Putative 4-carboxymuconolactone decarboxylase protein.
 
 
 0.998
pcaH
Probable protocatechuate 3,4-dioxygenase (beta chain) oxidoreductase protein.
 
 
 0.985
pcaG
Probable protocatechuate 3,4-dioxygenase (alpha chain) oxidoreductase protein.
 
 
 0.984
purL
Phosphoribosylformylglycinamidine synthase; Phosphoribosylformylglycinamidine synthase involved in the purines biosynthetic pathway. Catalyzes the ATP-dependent conversion of formylglycinamide ribonucleotide (FGAR) and glutamine to yield formylglycinamidine ribonucleotide (FGAM) and glutamate.
  
  
 0.972
pcaD
Probable b-ketoadipate enol-lactone hydrolase transmembrane protein.
  
 0.966
RSp1472
Probable 4-carboxymuconolactone decarboxylase protein.
 
 
 0.948
RSc0631
Probable transmembrane protein.
 
 
 0.933
pcaD2
Probable b-ketoadipate enol-lactone hydrolase protein.
  
 0.857
guaA
Probable gmp synthase [glutamine-hydrolyzing] (glutamineamidotransferase) (gmp synthetase) protein; Catalyzes the synthesis of GMP from XMP.
 
  
 0.839
purA
Probable adenylosuccinate synthetase (imp--aspartate ligase)(adss) (ampsase) protein; Plays an important role in the de novo pathway of purine nucleotide biosynthesis. Catalyzes the first committed step in the biosynthesis of AMP from IMP; Belongs to the adenylosuccinate synthetase family.
 
 
 0.830
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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