STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
RSc2356Probable bifunctional: uroporphyrin-III c-methyltransferase and uroporphyrinogen-III synthase transmembrane protein. (695 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.999
hemY
Putative protein porphyrin biosynthesis.
  
 0.985
hemE
Probable uroporphyrinogen decarboxylase (uro-d) (upd) protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
  
 
 0.955
nirE
Putative uroporphyrinogen-III c-methyltransferase protein; Belongs to the precorrin methyltransferase family.
  
 
 0.948
cbiL
Probable precorrin-2 c20-methyltransferase protein; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
    
 0.918
hemB
Probable delta-aminolevulinic acid dehydratase protein; Belongs to the ALAD family.
  
 
 0.853
RSc0398
Hypothetical transmembrane protein.
 
  
 0.826
ppc
Probable phosphoenolpyruvate carboxylase (pepcase) (pepc) protein; Forms oxaloacetate, a four-carbon dicarboxylic acid source for the tricarboxylic acid cycle.
     
 0.708
RSc2985
Probable cytochrome c assembly; abc transporter protein.
 
  
 0.682
RSc2734
Probable response regulator transcription regulator protein.
 
   
 0.672
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.