STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
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[Homology]
Score
nirEPutative uroporphyrinogen-III c-methyltransferase protein; Belongs to the precorrin methyltransferase family. (269 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
 0.992
cbiL
Probable precorrin-2 c20-methyltransferase protein; Methylates precorrin-2 at the C-20 position to produce precorrin-3A.
 
 
 0.963
cysH
Probable 5' adenylylsulfate aps reductase protein; Reduction of activated sulfate into sulfite.
 
  
 0.960
cobH
Putative precorrin isomerase transmembrane protein.
  
 0.953
RSc2356
Probable bifunctional: uroporphyrin-III c-methyltransferase and uroporphyrinogen-III synthase transmembrane protein.
  
 
 0.949
hemE
Probable uroporphyrinogen decarboxylase (uro-d) (upd) protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
    
 0.944
cysI1
Probable sulfite reductase oxidoreductase protein; Belongs to the nitrite and sulfite reductase 4Fe-4S domain family.
 
  
 0.938
cysD
Putative sulfate adenylyltransferase subunit 2 protein.
 
  
 0.923
hemB
Probable delta-aminolevulinic acid dehydratase protein; Belongs to the ALAD family.
 
  
 0.918
cysI2
Probable sulfite reductase oxidoreductase protein.
 
  
 0.846
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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