STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
ogtProbable methylated-dna--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. (185 aa)    
Predicted Functional Partners:
RSc2505
Putative transcription regulator protein.
  
 0.991
RSc1168
Putative dna glycosylase protein.
 
  
 0.912
queG
Probable 4fe-4s cluster binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family.
      0.904
lpxB
Probable lipid-a-disaccharide synthase protein; Condensation of UDP-2,3-diacylglucosamine and 2,3- diacylglucosamine-1-phosphate to form lipid A disaccharide, a precursor of lipid A, a phosphorylated glycolipid that anchors the lipopolysaccharide to the outer membrane of the cell.
      0.899
alkA
Probable dna-3-methyladenine glycosylase protein.
 
  
 0.748
tag
Probable dna-3-methyladenine glycosylaseIprotein.
   
 0.731
RSc2571
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
 
  
 0.686
RSc2507
Probable transmembrane protein.
       0.558
RSc2504
Probable short-chain dehydrogenase/reductase sdr; oxidoreductase protein.
       0.524
ada
Probable ada regulatory of adaptative response contains: methylated-dna--protein-cysteine methyltransferase ec 2.1.1.63 o-6-methylguanine-dna transcription regulator.
 
  
0.411
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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