| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| folD | xseA | RSc1596 | RSc2527 | Methenyltetrahydrofolate cyclohydrolase; Catalyzes the oxidation of 5,10-methylenetetrahydrofolate to 5,10-methenyltetrahydrofolate and then the hydrolysis of 5,10- methenyltetrahydrofolate to 10-formyltetrahydrofolate. | Probable exodeoxyribonuclease vII large subunit (exonuclease vII large subunit) protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.941 |
| ispA | xseA | RSc2222 | RSc2527 | Probable geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | Probable exodeoxyribonuclease vII large subunit (exonuclease vII large subunit) protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.722 |
| ispA | xseB | RSc2222 | RSc2223 | Probable geranyltranstransferase (farnesyl-diphosphate synthase) protein; Belongs to the FPP/GGPP synthase family. | Probable exodeoxyribonuclease vII small subunit (exonuclease vII small subunit) protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.922 |
| lpxC | xseA | RSc2837 | RSc2527 | UDP-3-O-acyl-N-acetylglucosamine deacetylase; Catalyzes the hydrolysis of UDP-3-O-myristoyl-N- acetylglucosamine to form UDP-3-O-myristoylglucosamine and acetate, the committed step in lipid A biosynthesis; Belongs to the LpxC family. | Probable exodeoxyribonuclease vII large subunit (exonuclease vII large subunit) protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.706 |
| mfd | recJ | RSc1642 | RSc1115 | Probable transcription-repair coupling factor protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Probable single-stranded-dna-specific exonuclease protein. | 0.564 |
| mfd | recN | RSc1642 | RSc2651 | Probable transcription-repair coupling factor protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Probable dna repair protein; May be involved in recombinational repair of damaged DNA. | 0.622 |
| mfd | ruvA | RSc1642 | RSc0501 | Probable transcription-repair coupling factor protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Probable holliday junction dna helicase ruva protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.493 |
| mfd | xseA | RSc1642 | RSc2527 | Probable transcription-repair coupling factor protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Probable exodeoxyribonuclease vII large subunit (exonuclease vII large subunit) protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.591 |
| mfd | xseB | RSc1642 | RSc2223 | Probable transcription-repair coupling factor protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | Probable exodeoxyribonuclease vII small subunit (exonuclease vII small subunit) protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.412 |
| priA | recJ | RSc3302 | RSc1115 | Probable primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | Probable single-stranded-dna-specific exonuclease protein. | 0.578 |
| priA | recN | RSc3302 | RSc2651 | Probable primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | Probable dna repair protein; May be involved in recombinational repair of damaged DNA. | 0.472 |
| priA | xseA | RSc3302 | RSc2527 | Probable primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | Probable exodeoxyribonuclease vII large subunit (exonuclease vII large subunit) protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.580 |
| recJ | mfd | RSc1115 | RSc1642 | Probable single-stranded-dna-specific exonuclease protein. | Probable transcription-repair coupling factor protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.564 |
| recJ | priA | RSc1115 | RSc3302 | Probable single-stranded-dna-specific exonuclease protein. | Probable primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.578 |
| recJ | recN | RSc1115 | RSc2651 | Probable single-stranded-dna-specific exonuclease protein. | Probable dna repair protein; May be involved in recombinational repair of damaged DNA. | 0.464 |
| recJ | ruvA | RSc1115 | RSc0501 | Probable single-stranded-dna-specific exonuclease protein. | Probable holliday junction dna helicase ruva protein; The RuvA-RuvB complex in the presence of ATP renatures cruciform structure in supercoiled DNA with palindromic sequence, indicating that it may promote strand exchange reactions in homologous recombination. RuvAB is a helicase that mediates the Holliday junction migration by localized denaturation and reannealing. RuvA stimulates, in the presence of DNA, the weak ATPase activity of RuvB. | 0.409 |
| recJ | xseA | RSc1115 | RSc2527 | Probable single-stranded-dna-specific exonuclease protein. | Probable exodeoxyribonuclease vII large subunit (exonuclease vII large subunit) protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseA family. | 0.602 |
| recJ | xseB | RSc1115 | RSc2223 | Probable single-stranded-dna-specific exonuclease protein. | Probable exodeoxyribonuclease vII small subunit (exonuclease vII small subunit) protein; Bidirectionally degrades single-stranded DNA into large acid- insoluble oligonucleotides, which are then degraded further into small acid-soluble oligonucleotides; Belongs to the XseB family. | 0.429 |
| recN | mfd | RSc2651 | RSc1642 | Probable dna repair protein; May be involved in recombinational repair of damaged DNA. | Probable transcription-repair coupling factor protein; Couples transcription and DNA repair by recognizing RNA polymerase (RNAP) stalled at DNA lesions. Mediates ATP-dependent release of RNAP and its truncated transcript from the DNA, and recruitment of nucleotide excision repair machinery to the damaged site; In the C-terminal section; belongs to the helicase family. RecG subfamily. | 0.622 |
| recN | priA | RSc2651 | RSc3302 | Probable dna repair protein; May be involved in recombinational repair of damaged DNA. | Probable primosomal protein n' (replication factor y); Involved in the restart of stalled replication forks. Recognizes and binds the arrested nascent DNA chain at stalled replication forks. It can open the DNA duplex, via its helicase activity, and promote assembly of the primosome and loading of the major replicative helicase DnaB onto DNA; Belongs to the helicase family. PriA subfamily. | 0.472 |