| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc2540 | amiC | RSc2540 | RSc2539 | Putative atpase or kinase protein. | Probable n-acetylmuramoyl-l-alanine amidase amic precursor protein. | 0.870 |
| RSc2540 | nnrD | RSc2540 | RSc1720 | Putative atpase or kinase protein. | Putative sugar kinase protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | 0.744 |
| RSc2540 | queG | RSc2540 | RSc2541 | Putative atpase or kinase protein. | Probable 4fe-4s cluster binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.756 |
| RSc2566 | ada | RSc2566 | RSc2570 | Putative methylated-dna--protein-cysteine methyltransferase. | Probable ada regulatory of adaptative response contains: methylated-dna--protein-cysteine methyltransferase ec 2.1.1.63 o-6-methylguanine-dna transcription regulator. | 0.653 |
| RSc2566 | queG | RSc2566 | RSc2541 | Putative methylated-dna--protein-cysteine methyltransferase. | Probable 4fe-4s cluster binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.715 |
| RSp0485 | queG | RSp0485 | RSc2541 | Putative hydrolase phosphatase protein. | Probable 4fe-4s cluster binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.580 |
| acpD | queG | RSp1258 | RSc2541 | Putative acyl carrier protein phosphodiesterase (acpphosphodiesterase); Catalyzes the reductive cleavage of azo bond in aromatic azo compounds to the corresponding amines. Requires NADH, but not NADPH, as an electron donor for its activity.; Belongs to the azoreductase type 1 family. | Probable 4fe-4s cluster binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.527 |
| ada | RSc2566 | RSc2570 | RSc2566 | Probable ada regulatory of adaptative response contains: methylated-dna--protein-cysteine methyltransferase ec 2.1.1.63 o-6-methylguanine-dna transcription regulator. | Putative methylated-dna--protein-cysteine methyltransferase. | 0.653 |
| ada | ogt | RSc2570 | RSc2506 | Probable ada regulatory of adaptative response contains: methylated-dna--protein-cysteine methyltransferase ec 2.1.1.63 o-6-methylguanine-dna transcription regulator. | Probable methylated-dna--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | 0.407 |
| ada | queG | RSc2570 | RSc2541 | Probable ada regulatory of adaptative response contains: methylated-dna--protein-cysteine methyltransferase ec 2.1.1.63 o-6-methylguanine-dna transcription regulator. | Probable 4fe-4s cluster binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.594 |
| amiC | RSc2540 | RSc2539 | RSc2540 | Probable n-acetylmuramoyl-l-alanine amidase amic precursor protein. | Putative atpase or kinase protein. | 0.870 |
| amiC | nnrD | RSc2539 | RSc1720 | Probable n-acetylmuramoyl-l-alanine amidase amic precursor protein. | Putative sugar kinase protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | 0.658 |
| amiC | queG | RSc2539 | RSc2541 | Probable n-acetylmuramoyl-l-alanine amidase amic precursor protein. | Probable 4fe-4s cluster binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.693 |
| nnrD | RSc2540 | RSc1720 | RSc2540 | Putative sugar kinase protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Putative atpase or kinase protein. | 0.744 |
| nnrD | amiC | RSc1720 | RSc2539 | Putative sugar kinase protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Probable n-acetylmuramoyl-l-alanine amidase amic precursor protein. | 0.658 |
| nnrD | queG | RSc1720 | RSc2541 | Putative sugar kinase protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Probable 4fe-4s cluster binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.604 |
| ogt | ada | RSc2506 | RSc2570 | Probable methylated-dna--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Probable ada regulatory of adaptative response contains: methylated-dna--protein-cysteine methyltransferase ec 2.1.1.63 o-6-methylguanine-dna transcription regulator. | 0.407 |
| ogt | queG | RSc2506 | RSc2541 | Probable methylated-dna--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated. | Probable 4fe-4s cluster binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.904 |
| queA | queF | RSc2712 | RSc0448 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Putative gtp cyclohydrolaseI protein; Catalyzes the NADPH-dependent reduction of 7-cyano-7- deazaguanine (preQ0) to 7-aminomethyl-7-deazaguanine (preQ1). | 0.639 |
| queA | queG | RSc2712 | RSc2541 | S-adenosylmethionine:tRNA ribosyltransferase-isomerase; Transfers and isomerizes the ribose moiety from AdoMet to the 7-aminomethyl group of 7-deazaguanine (preQ1-tRNA) to give epoxyqueuosine (oQ-tRNA). | Probable 4fe-4s cluster binding; Catalyzes the conversion of epoxyqueuosine (oQ) to queuosine (Q), which is a hypermodified base found in the wobble positions of tRNA(Asp), tRNA(Asn), tRNA(His) and tRNA(Tyr); Belongs to the QueG family. | 0.791 |