| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0511 | murA | RSc0511 | RSc2953 | Conserved hypothetical protein; Miscellaneous; hypothetical/global homology. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.816 |
| RSc0511 | murB | RSc0511 | RSc2550 | Conserved hypothetical protein; Miscellaneous; hypothetical/global homology. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.903 |
| RSc0511 | murC | RSc0511 | RSc2843 | Conserved hypothetical protein; Miscellaneous; hypothetical/global homology. | Probable udp-n-acetylmuramate--l-alanine ligase (udp-n-acetylmuramoyl-l-alanine synthetase) protein; Cell wall formation; Belongs to the MurCDEF family. | 0.807 |
| dapB | murB | RSc2745 | RSc2550 | Probable dihydrodipicolinate reductase (dhpr). oxidoreductase protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.792 |
| dapB | murC | RSc2745 | RSc2843 | Probable dihydrodipicolinate reductase (dhpr). oxidoreductase protein; Catalyzes the conversion of 4-hydroxy-tetrahydrodipicolinate (HTPA) to tetrahydrodipicolinate. | Probable udp-n-acetylmuramate--l-alanine ligase (udp-n-acetylmuramoyl-l-alanine synthetase) protein; Cell wall formation; Belongs to the MurCDEF family. | 0.441 |
| ddl | glmU | RSc2842 | RSc0177 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | Probable udp-n-acetylglucosamine pyrophosphorylase protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat [...] | 0.754 |
| ddl | murA | RSc2842 | RSc2953 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.873 |
| ddl | murB | RSc2842 | RSc2550 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.929 |
| ddl | murC | RSc2842 | RSc2843 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | Probable udp-n-acetylmuramate--l-alanine ligase (udp-n-acetylmuramoyl-l-alanine synthetase) protein; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
| ddl | murD | RSc2842 | RSc2846 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.993 |
| ddl | murE | RSc2842 | RSc2849 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.984 |
| ddl | murG | RSc2842 | RSc2844 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.995 |
| ddl | murI | RSc2842 | RSc1956 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | Probable glutamate racemase protein; Provides the (R)-glutamate required for cell wall biosynthesis. | 0.739 |
| glmU | ddl | RSc0177 | RSc2842 | Probable udp-n-acetylglucosamine pyrophosphorylase protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat [...] | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | 0.754 |
| glmU | murA | RSc0177 | RSc2953 | Probable udp-n-acetylglucosamine pyrophosphorylase protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat [...] | UDP-N-acetylglucosamine 1-carboxyvinyltransferase; Cell wall formation. Adds enolpyruvyl to UDP-N- acetylglucosamine; Belongs to the EPSP synthase family. MurA subfamily. | 0.977 |
| glmU | murB | RSc0177 | RSc2550 | Probable udp-n-acetylglucosamine pyrophosphorylase protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat [...] | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.754 |
| glmU | murC | RSc0177 | RSc2843 | Probable udp-n-acetylglucosamine pyrophosphorylase protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat [...] | Probable udp-n-acetylmuramate--l-alanine ligase (udp-n-acetylmuramoyl-l-alanine synthetase) protein; Cell wall formation; Belongs to the MurCDEF family. | 0.892 |
| glmU | murD | RSc0177 | RSc2846 | Probable udp-n-acetylglucosamine pyrophosphorylase protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat [...] | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.791 |
| glmU | murE | RSc0177 | RSc2849 | Probable udp-n-acetylglucosamine pyrophosphorylase protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat [...] | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.965 |
| glmU | murG | RSc0177 | RSc2844 | Probable udp-n-acetylglucosamine pyrophosphorylase protein; Catalyzes the last two sequential reactions in the de novo biosynthetic pathway for UDP-N-acetylglucosamine (UDP-GlcNAc). The C- terminal domain catalyzes the transfer of acetyl group from acetyl coenzyme A to glucosamine-1-phosphate (GlcN-1-P) to produce N- acetylglucosamine-1-phosphate (GlcNAc-1-P), which is converted into UDP-GlcNAc by the transfer of uridine 5-monophosphate (from uridine 5- triphosphate), a reaction catalyzed by the N-terminal domain. In the C-terminal section; belongs to the transferase hexapeptide repeat [...] | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.810 |