STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
alkAProbable dna-3-methyladenine glycosylase protein. (212 aa)    
Predicted Functional Partners:
RSc1168
Putative dna glycosylase protein.
  
  
 
0.919
RSc2505
Putative transcription regulator protein.
 
  
0.914
alkB
Probable alkylated dna repair protein.
     
 0.825
xthA
Probable exodeoxyribonuclease III protein.
  
 0.815
RSc2566
Putative methylated-dna--protein-cysteine methyltransferase.
  
  
 0.805
ada
Probable ada regulatory of adaptative response contains: methylated-dna--protein-cysteine methyltransferase ec 2.1.1.63 o-6-methylguanine-dna transcription regulator.
 
  
 0.805
RSc2567
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
       0.769
ogt
Probable methylated-dna--protein-cysteine methyltransferase; Involved in the cellular defense against the biological effects of O6-methylguanine (O6-MeG) and O4-methylthymine (O4-MeT) in DNA. Repairs the methylated nucleobase in DNA by stoichiometrically transferring the methyl group to a cysteine residue in the enzyme. This is a suicide reaction: the enzyme is irreversibly inactivated.
 
  
 0.748
dinB
Probable dna polymerase iv (pol iv) protein; Poorly processive, error-prone DNA polymerase involved in untargeted mutagenesis. Copies undamaged DNA at stalled replication forks, which arise in vivo from mismatched or misaligned primer ends. These misaligned primers can be extended by PolIV. Exhibits no 3'-5' exonuclease (proofreading) activity. May be involved in translesional synthesis, in conjunction with the beta clamp from PolIII.
  
 
 0.727
RSc2571
Conserved hypothetical protein; Miscellaneous; hypothetical/global homology.
     
 0.591
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.