STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
panB3-methyl-2-oxobutanoate hydroxymethyltransferase; Catalyzes the reversible reaction in which hydroxymethyl group from 5,10-methylenetetrahydrofolate is transferred onto alpha- ketoisovalerate to form ketopantoate; Belongs to the PanB family. (274 aa)    
Predicted Functional Partners:
panC
Pantothenate synthetase; Catalyzes the condensation of pantoate with beta-alanine in an ATP-dependent reaction via a pantoyl-adenylate intermediate. Belongs to the pantothenate synthetase family.
  
 0.999
panD
Aspartate 1-decarboxylase alpha chain; Catalyzes the pyruvoyl-dependent decarboxylation of aspartate to produce beta-alanine.
 
  
 0.980
ilvE3
Probable branched-chain amino acid aminotransferase protein.
 
  
 0.923
ilvD
Probable dihydroxy-acid dehydratase protein; Belongs to the IlvD/Edd family.
     
 0.920
RSc0174
Probable ketopantoate reductase apba/pane; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.916
folK
Probable 2-amino-4-hydroxy-6-hydroxymethyldihydropteridine pyrophosphokinase, 8-dihydro-6-hydroxymethylpterin-pyrophosphokinase protein.
  
 0.916
RSc3361
Probable ketopantoate reductase oxidoreductase protein.
    
 0.916
RSp1244
Putative ketopantoate reductase oxidoreductase protein; Catalyzes the NADPH-dependent reduction of ketopantoate into pantoic acid.
    
 0.916
ilvE
Probable branched-chain amino acid aminotransferase protein; Acts on leucine, isoleucine and valine. Belongs to the class-IV pyridoxal-phosphate-dependent aminotransferase family.
    
 0.912
RSc2631
Probable transmembrane abc transporter protein.
  
    0.758
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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