| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0168 | RSp0625 | RSc0168 | RSp0625 | Putative amine oxidase protein. | Probable magnesium chelatase (subunits dI protein. | 0.565 |
| RSc0168 | hemE | RSc0168 | RSc3303 | Putative amine oxidase protein. | Probable uroporphyrinogen decarboxylase (uro-d) (upd) protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.716 |
| RSc0168 | hemH | RSc0168 | RSc2643 | Putative amine oxidase protein. | Probable ferrochelatase (protoheme ferro-lyase) (hemesynthetase) protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.709 |
| RSc2740 | RSp0625 | RSc2740 | RSp0625 | Probable transmembrane protein. | Probable magnesium chelatase (subunits dI protein. | 0.920 |
| RSc2740 | hemE | RSc2740 | RSc3303 | Probable transmembrane protein. | Probable uroporphyrinogen decarboxylase (uro-d) (upd) protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.460 |
| RSc2740 | hemF | RSc2740 | RSc2192 | Probable transmembrane protein. | Oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.951 |
| RSc2740 | hemH | RSc2740 | RSc2643 | Probable transmembrane protein. | Probable ferrochelatase (protoheme ferro-lyase) (hemesynthetase) protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.954 |
| RSp0625 | RSc0168 | RSp0625 | RSc0168 | Probable magnesium chelatase (subunits dI protein. | Putative amine oxidase protein. | 0.565 |
| RSp0625 | RSc2740 | RSp0625 | RSc2740 | Probable magnesium chelatase (subunits dI protein. | Probable transmembrane protein. | 0.920 |
| RSp0625 | hemB | RSp0625 | RSc2989 | Probable magnesium chelatase (subunits dI protein. | Probable delta-aminolevulinic acid dehydratase protein; Belongs to the ALAD family. | 0.416 |
| RSp0625 | hemC | RSp0625 | RSc2357 | Probable magnesium chelatase (subunits dI protein. | Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family. | 0.703 |
| RSp0625 | hemE | RSp0625 | RSc3303 | Probable magnesium chelatase (subunits dI protein. | Probable uroporphyrinogen decarboxylase (uro-d) (upd) protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III. | 0.542 |
| RSp0625 | hemF | RSp0625 | RSc2192 | Probable magnesium chelatase (subunits dI protein. | Oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.415 |
| RSp0625 | hemH | RSp0625 | RSc2643 | Probable magnesium chelatase (subunits dI protein. | Probable ferrochelatase (protoheme ferro-lyase) (hemesynthetase) protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.950 |
| bfr | hemB | RSc0350 | RSc2989 | Probable bacterioferritin bfr (cytochrome b-1) (cytochrome b-557) protein; Iron-storage protein. | Probable delta-aminolevulinic acid dehydratase protein; Belongs to the ALAD family. | 0.502 |
| bfr | hemH | RSc0350 | RSc2643 | Probable bacterioferritin bfr (cytochrome b-1) (cytochrome b-557) protein; Iron-storage protein. | Probable ferrochelatase (protoheme ferro-lyase) (hemesynthetase) protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.934 |
| ctaB | hemF | RSc0372 | RSc2192 | Probable protoheme ix farnesyltransferase (heme o synthase) transmembrane protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX. | 0.483 |
| ctaB | hemH | RSc0372 | RSc2643 | Probable protoheme ix farnesyltransferase (heme o synthase) transmembrane protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group. | Probable ferrochelatase (protoheme ferro-lyase) (hemesynthetase) protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. | 0.936 |
| hemB | RSp0625 | RSc2989 | RSp0625 | Probable delta-aminolevulinic acid dehydratase protein; Belongs to the ALAD family. | Probable magnesium chelatase (subunits dI protein. | 0.416 |
| hemB | bfr | RSc2989 | RSc0350 | Probable delta-aminolevulinic acid dehydratase protein; Belongs to the ALAD family. | Probable bacterioferritin bfr (cytochrome b-1) (cytochrome b-557) protein; Iron-storage protein. | 0.502 |