STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hemHProbable ferrochelatase (protoheme ferro-lyase) (hemesynthetase) protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family. (371 aa)    
Predicted Functional Partners:
RSp0625
Probable magnesium chelatase (subunits dI protein.
  
 
 0.952
RSc2740
Probable transmembrane protein.
 
  
 0.950
ctaB
Probable protoheme ix farnesyltransferase (heme o synthase) transmembrane protein; Converts heme B (protoheme IX) to heme O by substitution of the vinyl group on carbon 2 of heme B porphyrin ring with a hydroxyethyl farnesyl side group.
     
 0.928
bfr
Probable bacterioferritin bfr (cytochrome b-1) (cytochrome b-557) protein; Iron-storage protein.
     
 0.923
hemE
Probable uroporphyrinogen decarboxylase (uro-d) (upd) protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
  
 0.909
hslR
Putative heat shock protein 15.
       0.840
cyaY
Probable protein cyay; Involved in iron-sulfur (Fe-S) cluster assembly. May act as a regulator of Fe-S biogenesis.
    
 
 0.834
hemF
Oxygen-dependent coproporphyrinogen-III oxidase; Involved in the heme biosynthesis. Catalyzes the aerobic oxidative decarboxylation of propionate groups of rings A and B of coproporphyrinogen-III to yield the vinyl groups in protoporphyrinogen- IX.
 
  
 0.808
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
  
  
 0.749
hemB
Probable delta-aminolevulinic acid dehydratase protein; Belongs to the ALAD family.
 
  
 0.731
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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