| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0950 | hisD | RSc0950 | RSc2952 | Hypothetical h^pothetical protein. | Probable histidinol dehydrogenase (hdh). oxidoreductase protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.900 |
| RSc0950 | hutH1 | RSc0950 | RSc2646 | Hypothetical h^pothetical protein. | Probable histidine ammonia-lyase (histidase) protein; Belongs to the PAL/histidase family. | 0.900 |
| RSc0950 | hutH2 | RSc0950 | RSp0365 | Hypothetical h^pothetical protein. | Probable histidine ammonia-lyase protein. | 0.900 |
| argC | gcvP | RSc0142 | RSc3295 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | 0.644 |
| argC | hisD | RSc0142 | RSc2952 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | Probable histidinol dehydrogenase (hdh). oxidoreductase protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | 0.542 |
| argC | hutH1 | RSc0142 | RSc2646 | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | Probable histidine ammonia-lyase (histidase) protein; Belongs to the PAL/histidase family. | 0.707 |
| gcvP | argC | RSc3295 | RSc0142 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | 0.644 |
| gcvP | hutH1 | RSc3295 | RSc2646 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Probable histidine ammonia-lyase (histidase) protein; Belongs to the PAL/histidase family. | 0.738 |
| gcvP | hutH2 | RSc3295 | RSp0365 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Probable histidine ammonia-lyase protein. | 0.534 |
| gcvP | hutU | RSc3295 | RSc2647 | Glycine dehydrogenase (decarboxylating); The glycine cleavage system catalyzes the degradation of glycine. The P protein binds the alpha-amino group of glycine through its pyridoxal phosphate cofactor; CO(2) is released and the remaining methylamine moiety is then transferred to the lipoamide cofactor of the H protein; Belongs to the GcvP family. | Probable urocanate hydratase (urocanase) (imidazolonepropionatehydrolase) protein; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. | 0.665 |
| hisD | RSc0950 | RSc2952 | RSc0950 | Probable histidinol dehydrogenase (hdh). oxidoreductase protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | Hypothetical h^pothetical protein. | 0.900 |
| hisD | argC | RSc2952 | RSc0142 | Probable histidinol dehydrogenase (hdh). oxidoreductase protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | N-acetyl-gamma-glutamyl-phosphate reductase; Catalyzes the NADPH-dependent reduction of N-acetyl-5- glutamyl phosphate to yield N-acetyl-L-glutamate 5-semialdehyde. Belongs to the NAGSA dehydrogenase family. Type 2 subfamily. | 0.542 |
| hisD | hutH1 | RSc2952 | RSc2646 | Probable histidinol dehydrogenase (hdh). oxidoreductase protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | Probable histidine ammonia-lyase (histidase) protein; Belongs to the PAL/histidase family. | 0.920 |
| hisD | hutH2 | RSc2952 | RSp0365 | Probable histidinol dehydrogenase (hdh). oxidoreductase protein; Catalyzes the sequential NAD-dependent oxidations of L- histidinol to L-histidinaldehyde and then to L-histidine. | Probable histidine ammonia-lyase protein. | 0.920 |
| hrcA | hutH1 | RSc2649 | RSc2646 | Probable heat-inducible transcription repressor hrca. transcription regulator protein; Negative regulator of class I heat shock genes (grpE-dnaK- dnaJ and groELS operons). Prevents heat-shock induction of these operons. | Probable histidine ammonia-lyase (histidase) protein; Belongs to the PAL/histidase family. | 0.690 |
| hutC | hutG | RSc2648 | RSc2645 | Probable histidine utilization repressor transcription regulator protein. | Probable formimidoylglutamase (formiminoglutamase)(formiminoglutamate hydrolase) protein; Catalyzes the conversion of N-formimidoyl-L-glutamate to L- glutamate and formamide; Belongs to the arginase family. | 0.668 |
| hutC | hutH1 | RSc2648 | RSc2646 | Probable histidine utilization repressor transcription regulator protein. | Probable histidine ammonia-lyase (histidase) protein; Belongs to the PAL/histidase family. | 0.884 |
| hutC | hutH2 | RSc2648 | RSp0365 | Probable histidine utilization repressor transcription regulator protein. | Probable histidine ammonia-lyase protein. | 0.601 |
| hutC | hutI | RSc2648 | RSc2644 | Probable histidine utilization repressor transcription regulator protein. | Probable imidazolonepropionase (imidazolone-5-propionatehydrolase). transmembrane protein; Belongs to the metallo-dependent hydrolases superfamily. HutI family. | 0.935 |
| hutC | hutU | RSc2648 | RSc2647 | Probable histidine utilization repressor transcription regulator protein. | Probable urocanate hydratase (urocanase) (imidazolonepropionatehydrolase) protein; Catalyzes the conversion of urocanate to 4-imidazolone-5- propionate. | 0.913 |