node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSc2655 | RSc2657 | RSc2655 | RSc2657 | Probable transmembrane protein. | Probable transmembrane protein. | 0.627 |
RSc2655 | RSc2658 | RSc2655 | RSc2658 | Probable transmembrane protein. | Putative protein of unknown function upf0012. | 0.526 |
RSc2655 | glnE | RSc2655 | RSc2656 | Probable transmembrane protein. | Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] | 0.795 |
RSc2655 | tldD | RSc2655 | RSc2659 | Probable transmembrane protein. | Putative zn-dependent protease protein. | 0.454 |
RSc2657 | RSc2655 | RSc2657 | RSc2655 | Probable transmembrane protein. | Probable transmembrane protein. | 0.627 |
RSc2657 | RSc2658 | RSc2657 | RSc2658 | Probable transmembrane protein. | Putative protein of unknown function upf0012. | 0.841 |
RSc2657 | glnE | RSc2657 | RSc2656 | Probable transmembrane protein. | Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] | 0.657 |
RSc2657 | tldD | RSc2657 | RSc2659 | Probable transmembrane protein. | Putative zn-dependent protease protein. | 0.792 |
RSc2658 | RSc2655 | RSc2658 | RSc2655 | Putative protein of unknown function upf0012. | Probable transmembrane protein. | 0.526 |
RSc2658 | RSc2657 | RSc2658 | RSc2657 | Putative protein of unknown function upf0012. | Probable transmembrane protein. | 0.841 |
RSc2658 | glnE | RSc2658 | RSc2656 | Putative protein of unknown function upf0012. | Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] | 0.665 |
RSc2658 | tldD | RSc2658 | RSc2659 | Putative protein of unknown function upf0012. | Putative zn-dependent protease protein. | 0.735 |
acdS | glnE | RSp0646 | RSc2656 | Probable 1-aminocyclopropane-1-carboxylate deaminase (accdeaminase) (accd) protein; Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source; Belongs to the ACC deaminase/D-cysteine desulfhydrase family. | Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] | 0.631 |
acdS | lrp | RSp0646 | RSc0927 | Probable 1-aminocyclopropane-1-carboxylate deaminase (accdeaminase) (accd) protein; Catalyzes a cyclopropane ring-opening reaction, the irreversible conversion of 1-aminocyclopropane-1-carboxylate (ACC) to ammonia and alpha-ketobutyrate. Allows growth on ACC as a nitrogen source; Belongs to the ACC deaminase/D-cysteine desulfhydrase family. | Probable leucine-responsive regulatory dna-binding transcription regulator protein. | 0.662 |
glnA1 | glnD | RSc1258 | RSc1402 | Probable glutamine synthetase protein. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.530 |
glnA1 | glnE | RSc1258 | RSc2656 | Probable glutamine synthetase protein. | Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] | 0.769 |
glnA2 | glnD | RSp0886 | RSc1402 | Probable glutamine synthetase protein. | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | 0.449 |
glnA2 | glnE | RSp0886 | RSc2656 | Probable glutamine synthetase protein. | Bifunctional glutamine synthetase adenylyltransferase/adenylyl-removing enzyme; Involved in the regulation of glutamine synthetase GlnA, a key enzyme in the process to assimilate ammonia. When cellular nitrogen levels are high, the C-terminal adenylyl transferase (AT) inactivates GlnA by covalent transfer of an adenylyl group from ATP to specific tyrosine residue of GlnA, thus reducing its activity. Conversely, when nitrogen levels are low, the N-terminal adenylyl removase (AR) activates GlnA by removing the adenylyl group by phosphorolysis, increasing its activity. The regulatory regi [...] | 0.741 |
glnD | glnA1 | RSc1402 | RSc1258 | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | Probable glutamine synthetase protein. | 0.530 |
glnD | glnA2 | RSc1402 | RSp0886 | Bifunctional uridylyltransferase/uridylyl-removing enzyme; Modifies, by uridylylation and deuridylylation, the PII regulatory proteins (GlnB and homologs), in response to the nitrogen status of the cell that GlnD senses through the glutamine level. Under low glutamine levels, catalyzes the conversion of the PII proteins and UTP to PII-UMP and PPi, while under higher glutamine levels, GlnD hydrolyzes PII-UMP to PII and UMP (deuridylylation). Thus, controls uridylylation state and activity of the PII proteins, and plays an important role in the regulation of nitrogen assimilation and met [...] | Probable glutamine synthetase protein. | 0.449 |