node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
RSc0344 | oxaA | RSc0344 | RSc0004 | Hypothetical glutamate--cysteine ligase related protein. | Putative preprotein translocase subunit yidc transmembrane; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.810 |
RSc0344 | polA | RSc0344 | RSc2230 | Hypothetical glutamate--cysteine ligase related protein. | Probable dna polymeraseIprotein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.482 |
RSc0344 | secE | RSc0344 | RSc3040 | Hypothetical glutamate--cysteine ligase related protein. | Putative preprotein translocase (sece subunit) transmembrane; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.719 |
RSc0344 | secF | RSc0344 | RSc2716 | Hypothetical glutamate--cysteine ligase related protein. | Probable-export membrane transmembrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.925 |
RSc0344 | secG | RSc0344 | RSc2063 | Hypothetical glutamate--cysteine ligase related protein. | Putative-export membrane protein secg (translocase) transmembrane; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.729 |
RSc0344 | secY | RSc0344 | RSc2999 | Hypothetical glutamate--cysteine ligase related protein. | Probable preprotein translocase secy (membrane subunit) transmembrane; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may [...] | 0.718 |
RSc0344 | yajC | RSc0344 | RSc2714 | Hypothetical glutamate--cysteine ligase related protein. | Probable preprotein translocase subunit yajc transmembrane; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.612 |
lepB | oxaA | RSc1061 | RSc0004 | Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family. | Putative preprotein translocase subunit yidc transmembrane; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | 0.798 |
lepB | secD | RSc1061 | RSc2715 | Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family. | Probable-export membrane protein secd transmembrane; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.543 |
lepB | secF | RSc1061 | RSc2716 | Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family. | Probable-export membrane transmembrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.575 |
lepB | secG | RSc1061 | RSc2063 | Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family. | Putative-export membrane protein secg (translocase) transmembrane; Involved in protein export. Participates in an early event of protein translocation; Belongs to the SecG family. | 0.557 |
lepB | secY | RSc1061 | RSc2999 | Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family. | Probable preprotein translocase secy (membrane subunit) transmembrane; The central subunit of the protein translocation channel SecYEG. Consists of two halves formed by TMs 1-5 and 6-10. These two domains form a lateral gate at the front which open onto the bilayer between TMs 2 and 7, and are clamped together by SecE at the back. The channel is closed by both a pore ring composed of hydrophobic SecY resides and a short helix (helix 2A) on the extracellular side of the membrane which forms a plug. The plug probably moves laterally to allow the channel to open. The ring and the pore may [...] | 0.841 |
oprM | secF | RSp0311 | RSc2716 | Probable outer membrane chanel lipoprotein. | Probable-export membrane transmembrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.783 |
oprM | yajC | RSp0311 | RSc2714 | Probable outer membrane chanel lipoprotein. | Probable preprotein translocase subunit yajc transmembrane; The SecYEG-SecDF-YajC-YidC holo-translocon (HTL) protein secretase/insertase is a supercomplex required for protein secretion, insertion of proteins into membranes, and assembly of membrane protein complexes. While the SecYEG complex is essential for assembly of a number of proteins and complexes, the SecDF-YajC-YidC subcomplex facilitates these functions. | 0.517 |
oxaA | RSc0344 | RSc0004 | RSc0344 | Putative preprotein translocase subunit yidc transmembrane; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | Hypothetical glutamate--cysteine ligase related protein. | 0.810 |
oxaA | lepB | RSc0004 | RSc1061 | Putative preprotein translocase subunit yidc transmembrane; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | Probable signal peptidaseI(spaseI transmembrane protein; Belongs to the peptidase S26 family. | 0.798 |
oxaA | polA | RSc0004 | RSc2230 | Putative preprotein translocase subunit yidc transmembrane; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | Probable dna polymeraseIprotein; In addition to polymerase activity, this DNA polymerase exhibits 5'-3' exonuclease activity; Belongs to the DNA polymerase type-A family. | 0.404 |
oxaA | secD | RSc0004 | RSc2715 | Putative preprotein translocase subunit yidc transmembrane; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | Probable-export membrane protein secd transmembrane; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.966 |
oxaA | secE | RSc0004 | RSc3040 | Putative preprotein translocase subunit yidc transmembrane; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | Putative preprotein translocase (sece subunit) transmembrane; Essential subunit of the Sec protein translocation channel SecYEG. Clamps together the 2 halves of SecY. May contact the channel plug during translocation; Belongs to the SecE/SEC61-gamma family. | 0.987 |
oxaA | secF | RSc0004 | RSc2716 | Putative preprotein translocase subunit yidc transmembrane; Required for the insertion and/or proper folding and/or complex formation of integral membrane proteins into the membrane. Involved in integration of membrane proteins that insert both dependently and independently of the Sec translocase complex, as well as at least some lipoproteins. Aids folding of multispanning membrane proteins. | Probable-export membrane transmembrane protein; Part of the Sec protein translocase complex. Interacts with the SecYEG preprotein conducting channel. SecDF uses the proton motive force (PMF) to complete protein translocation after the ATP-dependent function of SecA. | 0.817 |