STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
Neighborhood
Gene Fusion
Cooccurrence
Coexpression
Experiments
Databases
Textmining
[Homology]
Score
pyrFProbable orotidine 5'-phosphate decarboxylase (omp decarboxylase)(ompdcase) (ompdecase) protein; Belongs to the OMP decarboxylase family. Type 2 subfamily. (288 aa)    
Predicted Functional Partners:
pyrE
Orotate phosphoribosyltransferase protein; Catalyzes the transfer of a ribosyl phosphate group from 5- phosphoribose 1-diphosphate to orotate, leading to the formation of orotidine monophosphate (OMP).
 
 
 0.999
pyrR
Putative pyrr bifunctional protein [includes: pyrimidine operon regulatoryprotein; Regulates the transcription of the pyrimidine nucleotide (pyr) operon in response to exogenous pyrimidines.
  
 
 0.991
upp
Probable uracil phosphoribosyltransferase (ump pyrophosphorylase)(uprtase) protein; Catalyzes the conversion of uracil and 5-phospho-alpha-D- ribose 1-diphosphate (PRPP) to UMP and diphosphate.
  
 
 0.947
pyrB
Probable aspartate carbamoyltransferase (aspartatetranscarbamylase) (atcase) protein; Belongs to the aspartate/ornithine carbamoyltransferase superfamily. ATCase family.
  
  
 0.945
pyrX
Probable dihydroorotase-like protein.
  
  
 0.945
carB
Probable carbamoyl-phosphate synthase large chain (carbamoyl-phosphate synthetase ammonia chain) protein.
  
  
 0.945
pyrD
Probable dihydroorotate dehydrogenase oxidoreductase protein; Catalyzes the conversion of dihydroorotate to orotate with quinone as electron acceptor; Belongs to the dihydroorotate dehydrogenase family. Type 2 subfamily.
  
  
 0.945
carA
Probable carbamoyl-phosphate synthase small chain (carbamoyl-phosphate synthetase glutamine chain) protein; Belongs to the CarA family.
 
  
 0.944
pyrH
Probable uridylate kinase (uk) (uridine monophosphate kinase) (umpkinase) protein; Catalyzes the reversible phosphorylation of UMP to UDP.
   
 
 0.938
surE
Probable 5'-nucleotidase sure (nucleoside 5'-monophosphatephosphohydrolase) protein; Nucleotidase that shows phosphatase activity on nucleoside 5'-monophosphates; Belongs to the SurE nucleotidase family.
    
 0.922
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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