| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc1827 | RSp0038 | RSc1827 | RSp0038 | Probable thioesterase protein. | Probable thioesterase protein. | 0.905 |
| RSc1827 | ubiA | RSc1827 | RSc2686 | Probable thioesterase protein. | Probable 4-hydroxybenzoate octaprenyltransferase transmembrane protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.905 |
| RSc1827 | ubiC | RSc1827 | RSc2780 | Probable thioesterase protein. | Putative chorismate lyase protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.906 |
| RSp0038 | RSc1827 | RSp0038 | RSc1827 | Probable thioesterase protein. | Probable thioesterase protein. | 0.905 |
| RSp0038 | ubiA | RSp0038 | RSc2686 | Probable thioesterase protein. | Probable 4-hydroxybenzoate octaprenyltransferase transmembrane protein; Catalyzes the prenylation of para-hydroxybenzoate (PHB) with an all-trans polyprenyl group. Mediates the second step in the final reaction sequence of ubiquinone-8 (UQ-8) biosynthesis, which is the condensation of the polyisoprenoid side chain with PHB, generating the first membrane-bound Q intermediate 3-octaprenyl-4-hydroxybenzoate. | 0.905 |
| RSp0038 | ubiC | RSp0038 | RSc2780 | Probable thioesterase protein. | Putative chorismate lyase protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.906 |
| RSp0197 | aroC | RSp0197 | RSc1566 | Putative chorismate mutase protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Probable chorismate synthase (5-enolpyruvylshikimate-3-phosphatephospholyase) protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.962 |
| RSp0197 | pheA | RSp0197 | RSc0904 | Putative chorismate mutase protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Probable bifunctional protein: chorismate mutase and prephenate dehydratase. | 0.924 |
| RSp0197 | trpE | RSp0197 | RSc2881 | Putative chorismate mutase protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Probable anthranilate synthase componentIprotein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate an [...] | 0.915 |
| RSp0197 | trpG | RSp0197 | RSc2882 | Putative chorismate mutase protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Probable panthranilate synthase component II (glutamine amido-transferase) protein. | 0.921 |
| RSp0197 | tyrB | RSp0197 | RSc1010 | Putative chorismate mutase protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Probable aromatic-amino-acid aminotransferase protein. | 0.919 |
| RSp0197 | ubiC | RSp0197 | RSc2780 | Putative chorismate mutase protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. | Putative chorismate lyase protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.827 |
| aroC | RSp0197 | RSc1566 | RSp0197 | Probable chorismate synthase (5-enolpyruvylshikimate-3-phosphatephospholyase) protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Putative chorismate mutase protein; Catalyzes the Claisen rearrangement of chorismate to prephenate. | 0.962 |
| aroC | hisC2 | RSc1566 | RSc0905 | Probable chorismate synthase (5-enolpyruvylshikimate-3-phosphatephospholyase) protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Probable histidinol-phosphate aminotransferase 2 (imidazoleacetol-phosphate transaminase 2) protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | 0.617 |
| aroC | pheA | RSc1566 | RSc0904 | Probable chorismate synthase (5-enolpyruvylshikimate-3-phosphatephospholyase) protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Probable bifunctional protein: chorismate mutase and prephenate dehydratase. | 0.990 |
| aroC | trpE | RSc1566 | RSc2881 | Probable chorismate synthase (5-enolpyruvylshikimate-3-phosphatephospholyase) protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Probable anthranilate synthase componentIprotein; Part of a heterotetrameric complex that catalyzes the two- step biosynthesis of anthranilate, an intermediate in the biosynthesis of L-tryptophan. In the first step, the glutamine-binding beta subunit (TrpG) of anthranilate synthase (AS) provides the glutamine amidotransferase activity which generates ammonia as a substrate that, along with chorismate, is used in the second step, catalyzed by the large alpha subunit of AS (TrpE) to produce anthranilate. In the absence of TrpG, TrpE can synthesize anthranilate directly from chorismate an [...] | 0.977 |
| aroC | trpG | RSc1566 | RSc2882 | Probable chorismate synthase (5-enolpyruvylshikimate-3-phosphatephospholyase) protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Probable panthranilate synthase component II (glutamine amido-transferase) protein. | 0.971 |
| aroC | tyrB | RSc1566 | RSc1010 | Probable chorismate synthase (5-enolpyruvylshikimate-3-phosphatephospholyase) protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Probable aromatic-amino-acid aminotransferase protein. | 0.655 |
| aroC | ubiC | RSc1566 | RSc2780 | Probable chorismate synthase (5-enolpyruvylshikimate-3-phosphatephospholyase) protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | Putative chorismate lyase protein; Removes the pyruvyl group from chorismate, with concomitant aromatization of the ring, to provide 4-hydroxybenzoate (4HB) for the ubiquinone pathway; Belongs to the UbiC family. | 0.809 |
| hisC2 | aroC | RSc0905 | RSc1566 | Probable histidinol-phosphate aminotransferase 2 (imidazoleacetol-phosphate transaminase 2) protein; Belongs to the class-II pyridoxal-phosphate-dependent aminotransferase family. Histidinol-phosphate aminotransferase subfamily. | Probable chorismate synthase (5-enolpyruvylshikimate-3-phosphatephospholyase) protein; Catalyzes the anti-1,4-elimination of the C-3 phosphate and the C-6 proR hydrogen from 5-enolpyruvylshikimate-3-phosphate (EPSP) to yield chorismate, which is the branch point compound that serves as the starting substrate for the three terminal pathways of aromatic amino acid biosynthesis. This reaction introduces a second double bond into the aromatic ring system. | 0.617 |
