| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc0352 | nudH | RSc0352 | RSc2817 | Probable peptidase transmembrane protein; Belongs to the peptidase S41A family. | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.614 |
| RSc1787 | nudH | RSc1787 | RSc2817 | Putative tatd-related deoxyribonuclease; protein. | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.770 |
| RSc2779 | nudH | RSc2779 | RSc2817 | Putative ribonuclease protein. | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.628 |
| RSc2815 | RSc2818 | RSc2815 | RSc2818 | Putative transglycosylase signal peptide protein. | Putative lipoprotein. | 0.541 |
| RSc2815 | nudH | RSc2815 | RSc2817 | Putative transglycosylase signal peptide protein. | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.571 |
| RSc2818 | RSc2815 | RSc2818 | RSc2815 | Putative lipoprotein. | Putative transglycosylase signal peptide protein. | 0.541 |
| RSc2818 | nudH | RSc2818 | RSc2817 | Putative lipoprotein. | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.806 |
| dapF | nudH | RSc0137 | RSc2817 | Diaminopimelate epimerase (dap epimerase) protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.809 |
| hfq | nudH | RSc1220 | RSc2817 | Putative hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.567 |
| hfq | rnr | RSc1220 | RSc1228 | Putative hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Probable exoribonuclease rnase r (vacb protein); 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.601 |
| hfq | ybeY | RSc1220 | RSc0529 | Putative hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | Hypothetical protein; Single strand-specific metallo-endoribonuclease involved in late-stage 70S ribosome quality control and in maturation of the 3' terminus of the 16S rRNA. | 0.510 |
| nnrD | nudH | RSc1720 | RSc2817 | Putative sugar kinase protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | 0.832 |
| nnrD | rnr | RSc1720 | RSc1228 | Putative sugar kinase protein; Bifunctional enzyme that catalyzes the epimerization of the S- and R-forms of NAD(P)HX and the dehydration of the S-form of NAD(P)HX at the expense of ADP, which is converted to AMP. This allows the repair of both epimers of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. Catalyzes the epimerization of the S- and R-forms of NAD(P)HX, a damaged form of NAD(P)H that is a result of enzymatic or heat-dependent hydration. This is a prerequisite for the S-specific NAD(P)H-hydrate dehydratase to allow the repair of [...] | Probable exoribonuclease rnase r (vacb protein); 3'-5' exoribonuclease that releases 5'-nucleoside monophosphates and is involved in maturation of structured RNAs. | 0.440 |
| nudH | RSc0352 | RSc2817 | RSc0352 | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | Probable peptidase transmembrane protein; Belongs to the peptidase S41A family. | 0.614 |
| nudH | RSc1787 | RSc2817 | RSc1787 | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | Putative tatd-related deoxyribonuclease; protein. | 0.770 |
| nudH | RSc2779 | RSc2817 | RSc2779 | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | Putative ribonuclease protein. | 0.628 |
| nudH | RSc2815 | RSc2817 | RSc2815 | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | Putative transglycosylase signal peptide protein. | 0.571 |
| nudH | RSc2818 | RSc2817 | RSc2818 | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | Putative lipoprotein. | 0.806 |
| nudH | dapF | RSc2817 | RSc0137 | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | Diaminopimelate epimerase (dap epimerase) protein; Catalyzes the stereoinversion of LL-2,6-diaminoheptanedioate (L,L-DAP) to meso-diaminoheptanedioate (meso-DAP), a precursor of L- lysine and an essential component of the bacterial peptidoglycan. | 0.809 |
| nudH | hfq | RSc2817 | RSc1220 | Probable (di)nucleoside polyphosphate hydrolase protein; Accelerates the degradation of transcripts by removing pyrophosphate from the 5'-end of triphosphorylated RNA, leading to a more labile monophosphorylated state that can stimulate subsequent ribonuclease cleavage; Belongs to the Nudix hydrolase family. RppH subfamily. | Putative hfq protein; RNA chaperone that binds small regulatory RNA (sRNAs) and mRNAs to facilitate mRNA translational regulation in response to envelope stress, environmental stress and changes in metabolite concentrations. Also binds with high specificity to tRNAs. Belongs to the Hfq family. | 0.567 |