node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
ddl | ftsI | RSc2842 | RSc2850 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | 0.949 |
ddl | ftsQ | RSc2842 | RSc2841 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | Putative cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.977 |
ddl | ftsW | RSc2842 | RSc2845 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | Probable cell division ftsw transmembrane protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.964 |
ddl | mraY | RSc2842 | RSc2847 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | Phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.977 |
ddl | murB | RSc2842 | RSc2550 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.929 |
ddl | murC | RSc2842 | RSc2843 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | Probable udp-n-acetylmuramate--l-alanine ligase (udp-n-acetylmuramoyl-l-alanine synthetase) protein; Cell wall formation; Belongs to the MurCDEF family. | 0.999 |
ddl | murD | RSc2842 | RSc2846 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.993 |
ddl | murE | RSc2842 | RSc2849 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.984 |
ddl | murF | RSc2842 | RSc2848 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.999 |
ddl | murG | RSc2842 | RSc2844 | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.995 |
ftsI | ddl | RSc2850 | RSc2842 | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Probable d-alanine--d-alanine ligase (d-alanylalanine synthetase)(d-ala-d-ala ligase) protein; Cell wall formation. | 0.949 |
ftsI | ftsQ | RSc2850 | RSc2841 | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Putative cell division transmembrane protein; Essential cell division protein. May link together the upstream cell division proteins, which are predominantly cytoplasmic, with the downstream cell division proteins, which are predominantly periplasmic. May control correct divisome assembly. | 0.989 |
ftsI | ftsW | RSc2850 | RSc2845 | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Probable cell division ftsw transmembrane protein; Peptidoglycan polymerase that is essential for cell division. Belongs to the SEDS family. FtsW subfamily. | 0.995 |
ftsI | mraY | RSc2850 | RSc2847 | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Phospho-N-acetylmuramoyl-pentapeptide-transferase; First step of the lipid cycle reactions in the biosynthesis of the cell wall peptidoglycan; Belongs to the glycosyltransferase 4 family. MraY subfamily. | 0.989 |
ftsI | murB | RSc2850 | RSc2550 | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylenolpyruvoylglucosamine reductase; Cell wall formation. | 0.613 |
ftsI | murC | RSc2850 | RSc2843 | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Probable udp-n-acetylmuramate--l-alanine ligase (udp-n-acetylmuramoyl-l-alanine synthetase) protein; Cell wall formation; Belongs to the MurCDEF family. | 0.962 |
ftsI | murD | RSc2850 | RSc2846 | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramoylalanine--D-glutamate ligase; Cell wall formation. Catalyzes the addition of glutamate to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanine (UMA). Belongs to the MurCDEF family. | 0.982 |
ftsI | murE | RSc2850 | RSc2849 | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--2,6-diaminopimelate ligase; Catalyzes the addition of meso-diaminopimelic acid to the nucleotide precursor UDP-N-acetylmuramoyl-L-alanyl-D-glutamate (UMAG) in the biosynthesis of bacterial cell-wall peptidoglycan. Belongs to the MurCDEF family. MurE subfamily. | 0.993 |
ftsI | murF | RSc2850 | RSc2848 | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase; Involved in cell wall formation. Catalyzes the final step in the synthesis of UDP-N-acetylmuramoyl-pentapeptide, the precursor of murein; Belongs to the MurCDEF family. MurF subfamily. | 0.967 |
ftsI | murG | RSc2850 | RSc2844 | Probable penicillin-binding 3 precursor pbp-3 transmembrane protein; Catalyzes cross-linking of the peptidoglycan cell wall at the division septum; Belongs to the transpeptidase family. FtsI subfamily. | Undecaprenyl-PP-MurNAc-pentapeptide-UDPGlcNAc GlcNAc transferase; Cell wall formation. Catalyzes the transfer of a GlcNAc subunit on undecaprenyl-pyrophosphoryl-MurNAc-pentapeptide (lipid intermediate I) to form undecaprenyl-pyrophosphoryl-MurNAc- (pentapeptide)GlcNAc (lipid intermediate II); Belongs to the glycosyltransferase 28 family. MurG subfamily. | 0.954 |