| node1 | node2 | node1 accession | node2 accession | node1 annotation | node2 annotation | score |
| RSc2116 | msrP | RSc2116 | RSc2981 | Hypothetical transthyretin-like protein; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...] | 0.459 |
| RSc2116 | msrQ | RSc2116 | RSc2980 | Hypothetical transthyretin-like protein; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | Probable transmembrane protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, [...] | 0.660 |
| RSc2982 | RSc2984 | RSc2982 | RSc2984 | Probable cog5662, transmembrane transcriptional regulator (anti-sigma factor) transmembrane protein. | Probable transmembrane protein. | 0.905 |
| RSc2982 | msrP | RSc2982 | RSc2981 | Probable cog5662, transmembrane transcriptional regulator (anti-sigma factor) transmembrane protein. | Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...] | 0.542 |
| RSc2982 | msrQ | RSc2982 | RSc2980 | Probable cog5662, transmembrane transcriptional regulator (anti-sigma factor) transmembrane protein. | Probable transmembrane protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, [...] | 0.542 |
| RSc2982 | rpoE2 | RSc2982 | RSc2983 | Probable cog5662, transmembrane transcriptional regulator (anti-sigma factor) transmembrane protein. | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | 0.949 |
| RSc2984 | RSc2982 | RSc2984 | RSc2982 | Probable transmembrane protein. | Probable cog5662, transmembrane transcriptional regulator (anti-sigma factor) transmembrane protein. | 0.905 |
| RSc2984 | msrP | RSc2984 | RSc2981 | Probable transmembrane protein. | Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...] | 0.486 |
| RSc2984 | msrQ | RSc2984 | RSc2980 | Probable transmembrane protein. | Probable transmembrane protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. MsrQ provides electrons for reduction to the reductase catalytic subunit MsrP, [...] | 0.486 |
| RSc2984 | rpoE2 | RSc2984 | RSc2983 | Probable transmembrane protein. | Probable rna polymerase sigma-e factor (sigma-24) transcription regulator protein; Belongs to the sigma-70 factor family. ECF subfamily. | 0.779 |
| RSc3256 | coxM | RSc3256 | RSp1564 | Putative cytochrome c-related protein. | Probable cytochrome c oxidase polypeptide II (cytochrome bb3 subunit 2) transmembrane protein. | 0.594 |
| RSc3256 | msrP | RSc3256 | RSc2981 | Putative cytochrome c-related protein. | Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...] | 0.559 |
| RSp1453 | coxM | RSp1453 | RSp1564 | Putative cytochrome c signal peptide protein. | Probable cytochrome c oxidase polypeptide II (cytochrome bb3 subunit 2) transmembrane protein. | 0.646 |
| RSp1453 | msrP | RSp1453 | RSc2981 | Putative cytochrome c signal peptide protein. | Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...] | 0.583 |
| coxM | RSc3256 | RSp1564 | RSc3256 | Probable cytochrome c oxidase polypeptide II (cytochrome bb3 subunit 2) transmembrane protein. | Putative cytochrome c-related protein. | 0.594 |
| coxM | RSp1453 | RSp1564 | RSp1453 | Probable cytochrome c oxidase polypeptide II (cytochrome bb3 subunit 2) transmembrane protein. | Putative cytochrome c signal peptide protein. | 0.646 |
| coxM | msrP | RSp1564 | RSc2981 | Probable cytochrome c oxidase polypeptide II (cytochrome bb3 subunit 2) transmembrane protein. | Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...] | 0.616 |
| msrP | RSc2116 | RSc2981 | RSc2116 | Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...] | Hypothetical transthyretin-like protein; Catalyzes the hydrolysis of 5-hydroxyisourate (HIU) to 2-oxo- 4-hydroxy-4-carboxy-5-ureidoimidazoline (OHCU); Belongs to the transthyretin family. 5-hydroxyisourate hydrolase subfamily. | 0.459 |
| msrP | RSc2982 | RSc2981 | RSc2982 | Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...] | Probable cog5662, transmembrane transcriptional regulator (anti-sigma factor) transmembrane protein. | 0.542 |
| msrP | RSc2984 | RSc2981 | RSc2984 | Conserved hypothetical protein; Part of the MsrPQ system that repairs oxidized periplasmic proteins containing methionine sulfoxide residues (Met-O), using respiratory chain electrons. Thus protects these proteins from oxidative-stress damage caused by reactive species of oxygen and chlorine generated by the host defense mechanisms. MsrPQ is essential for the maintenance of envelope integrity under bleach stress, rescuing a wide series of structurally unrelated periplasmic proteins from methionine oxidation. The catalytic subunit MsrP is non-stereospecific, being able to reduce both (R [...] | Probable transmembrane protein. | 0.486 |