STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
Gene Fusion
Co-occurrence
Co-expression
Experiments
Databases
Textmining
[Homology]
Score
hemBProbable delta-aminolevulinic acid dehydratase protein; Belongs to the ALAD family. (331 aa)    
Predicted Functional Partners:
hemC
Porphobilinogen deaminase; Tetrapolymerization of the monopyrrole PBG into the hydroxymethylbilane pre-uroporphyrinogen in several discrete steps. Belongs to the HMBS family.
 
 0.998
hemL
Probable glutamate-1-semialdehyde 2,1-aminomutase protein.
 
 
 0.991
nirE
Putative uroporphyrinogen-III c-methyltransferase protein; Belongs to the precorrin methyltransferase family.
 
  
 0.917
hemA
Probable glutamyl-trna reductase oxidoreductase protein; Catalyzes the NADPH-dependent reduction of glutamyl-tRNA(Glu) to glutamate 1-semialdehyde (GSA).
 
  
 0.885
RSc2356
Probable bifunctional: uroporphyrin-III c-methyltransferase and uroporphyrinogen-III synthase transmembrane protein.
  
 
 0.853
hemE
Probable uroporphyrinogen decarboxylase (uro-d) (upd) protein; Catalyzes the decarboxylation of four acetate groups of uroporphyrinogen-III to yield coproporphyrinogen-III.
 
 
 0.853
cobA
Probable cobIalamin adenosyltransferase protein; Required for both de novo synthesis of the corrin ring for the assimilation of exogenous corrinoids. Participates in the adenosylation of a variety of incomplete and complete corrinoids.
     
 0.815
cobB
Probable cobyrinic acid a,c-diamide synthase protein; Catalyzes the ATP-dependent amidation of the two carboxylate groups at positions a and c of cobyrinate, using either L-glutamine or ammonia as the nitrogen source; Belongs to the CobB/CbiA family.
 
  
 0.765
cbiF
Probable precorrin-4 c11-methyltransferase protein; Belongs to the precorrin methyltransferase family.
 
   
 0.746
hemH
Probable ferrochelatase (protoheme ferro-lyase) (hemesynthetase) protein; Catalyzes the ferrous insertion into protoporphyrin IX. Belongs to the ferrochelatase family.
 
  
 0.731
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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