STRINGSTRING
STRING protein interaction network
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Knowledge-based Evidence
from curated databases
textmining
Assay-based Predictions
experimentally determined
co-expression
Genomic Predictions
gene neighborhood
gene co-occurrence
gene fusions
Your Input:
Neighborhood
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Co-occurrence
Co-expression
Experiments
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[Homology]
Score
ldhAPutative d-lactate dehydrogenase (d-ldh) oxidoreductase protein; Belongs to the D-isomer specific 2-hydroxyacid dehydrogenase family. (342 aa)    
Predicted Functional Partners:
maeB1
Putative nadp-dependent malic enzyme oxidoreductase protein.
   
 0.936
maeB2
Putative nadp-dependent malic enzyme oxidoreductase protein.
   
 0.936
pykA1
Probable pyruvate kinase II protein; Belongs to the pyruvate kinase family.
  
 0.927
pykA2
Probable pyruvate kinase II protein; Belongs to the pyruvate kinase family.
  
 0.927
dld
Putative d-lactate dehydrogenase (cytochrome) oxidoreductase protein.
   
 0.916
ppsA
Probable phosphoenolpyruvate synthase protein; Catalyzes the phosphorylation of pyruvate to phosphoenolpyruvate; Belongs to the PEP-utilizing enzyme family.
    
 0.913
gloB
Putative hydroxyacylglutathione hydrolase protein; Thiolesterase that catalyzes the hydrolysis of S-D-lactoyl- glutathione to form glutathione and D-lactic acid.
   
 
  0.904
aceE
Probable pyruvate dehydrogenase e1 component oxidoreductase protein; Component of the pyruvate dehydrogenase (PDH) complex, that catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2).
     
 0.904
RSc3268
Putative beta-lactamase-like protein.
   
 
  0.904
leuA1
2-isopropylmalate synthase 1; Catalyzes the condensation of the acetyl group of acetyl-CoA with 3-methyl-2-oxobutanoate (2-oxoisovalerate) to form 3-carboxy-3- hydroxy-4-methylpentanoate (2-isopropylmalate); Belongs to the alpha-IPM synthase/homocitrate synthase family. LeuA type 1 subfamily.
  
 
 0.814
Your Current Organism:
Ralstonia solanacearum
NCBI taxonomy Id: 267608
Other names: R. solanacearum GMI1000, Ralstonia solanacearum GMI1000, Ralstonia solanacearum str. GMI1000, Ralstonia solanacearum strain GMI1000
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